胃早癌患者内镜治疗前后血清胃蛋白酶原水平的变化和意义
发布时间：2018-08-07 07:40
【摘要】：探讨胃早癌患者血清胃蛋白酶原(PG)水平及内镜治疗前后的变化和意义。185例行内镜下黏膜切除术(EMR)或内镜下黏膜剥离术(ESD)的患者以及同时期胃镜检查阴性者90例、非萎缩性胃炎患者178例、萎缩性胃炎患者67例、胃溃疡患者46例进入到本研究。结果显示,与其他各组相比,早癌内镜治疗组患者血清PGⅠ和PGR(PGⅠ和PGⅡ的比值)显著降低。早癌内镜治疗组患者术后30天和90天的PGⅠ和PGR数值显著升高、PGⅡ数值显著降低。早癌内镜治疗组患者按照男女性别分组计算得出的术前、术后30天、术后90天PGⅠ、PGⅡ、PGR的数值,两组间各数值均无统计学差异(P0.05)。因此,PGⅠ和PGR可以用作胃早癌人群的筛查。胃早癌内镜治疗术后PG和PGR的数值随访可在预防监测胃癌有无复发上发挥作用,并可间接评价EMR和ESD内镜下治疗的有效性。PG和PGR作为胃早癌人群的筛查以及术后预防和监测指标,并不受性别影响。
[Abstract]:To investigate the changes and significance of serum pepsinogen (PG) level in patients with early gastric cancer and the changes before and after endoscopic treatment. 185 patients underwent endoscopic mucosal resection (EMR) or endoscopic mucosal dissection (ESD) and 90 patients with negative gastroscopy at the same time. 178 patients with non-atrophic gastritis, 67 patients with atrophic gastritis and 46 patients with gastric ulcer entered the study. The results showed that compared with other groups, the ratio of PG 鈪，
本文编号：2169331
[Abstract]:To investigate the changes and significance of serum pepsinogen (PG) level in patients with early gastric cancer and the changes before and after endoscopic treatment. 185 patients underwent endoscopic mucosal resection (EMR) or endoscopic mucosal dissection (ESD) and 90 patients with negative gastroscopy at the same time. 178 patients with non-atrophic gastritis, 67 patients with atrophic gastritis and 46 patients with gastric ulcer entered the study. The results showed that compared with other groups, the ratio of PG 鈪，
本文编号：2169331
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