卵巢子宫内膜异位症恶变的临床病理特征分析
发布时间：2018-08-25 14:59
【摘要】：目的:分析卵巢子宫内膜异位症(EMs)恶变的临床病理特征。方法:回顾分析2011年12月至2015年12月于郑州大学人民医院妇科行手术治疗且术后病理确诊的卵巢癌患者281例,其中符合内异症恶变诊断标准者24例(内异症恶变组),非内异症恶变者257例(非内异症恶变组)。分析两组患者的临床组织病理学类型及FIGO分期。结果:与非内异症恶变组相比,内异症恶变组患者的平均年龄早、绝经前诊断比例较大,差异均有统计学意义(P0.05)。内异症恶变组术前CA125值(110.27±112.62)U/ml,腹水量较少、病理类型多为透明细胞癌(45.83%)、FIGO分期早期(87.50%);非内异症恶变组术前CA125值(1242.75±2104.28)U/ml、腹水量较多,病理类型多为浆液性腺癌(72.37%),FIGO分期晚期(74.71%);两组比较,差异均有统计学意义(P均0.05)。两组患者在癌灶单双侧及淋巴结转移情况比较,差异均无统计学意义(P均0.05)。结论:卵巢内异症恶变患者发病年龄小、腹水量少、术前CA125较低、FIGO期别早,组织病理以透明细胞癌及子宫内膜样腺癌为主。
[Abstract]:Objective: to analyze the clinicopathological features of (EMs) malignancy in ovarian endometriosis. Methods: from December 2011 to December 2015, 281 patients with ovarian cancer treated by gynecologic surgery and confirmed by pathology in Renmin Hospital of Zhengzhou University were retrospectively analyzed. Among them, 24 cases were in accordance with the diagnostic criteria of malignant change of endometriosis (malignant change group) and 257 cases were non-malignant change group (non-malignant group). The clinicopathological types and FIGO staging of the two groups were analyzed. Results: compared with non-endometriosis group, the average age and premenopausal diagnosis of the patients were earlier and the difference was statistically significant (P0.05). The preoperative CA125 value was (110.27 卤112.62) U / ml, the quantity of ascites was less and the pathological type was clear cell carcinoma (45.83%) early stage of Figo stage (87.50%), the preoperative CA125 value was (1242.75 卤2104.28) U / ml, and the pathological type was serous adenocarcinoma (72.37%) late stage of Figo stage (74.71%). The difference was statistically significant (P 0.05). There was no significant difference between the two groups (P 0.05). Conclusion: the patients with malignant change of ovarian endometriosis are young in age, less in ascites, lower in CA125 before operation and earlier in Figo stage. The histopathology is mainly clear cell carcinoma and endometrial adenocarcinoma.
【作者单位】： 郑州大学人民医院;
【基金】：河南省医学科技攻关计划(No:201301007)
【分类号】：R737.31
，
本文编号：2203226
[Abstract]:Objective: to analyze the clinicopathological features of (EMs) malignancy in ovarian endometriosis. Methods: from December 2011 to December 2015, 281 patients with ovarian cancer treated by gynecologic surgery and confirmed by pathology in Renmin Hospital of Zhengzhou University were retrospectively analyzed. Among them, 24 cases were in accordance with the diagnostic criteria of malignant change of endometriosis (malignant change group) and 257 cases were non-malignant change group (non-malignant group). The clinicopathological types and FIGO staging of the two groups were analyzed. Results: compared with non-endometriosis group, the average age and premenopausal diagnosis of the patients were earlier and the difference was statistically significant (P0.05). The preoperative CA125 value was (110.27 卤112.62) U / ml, the quantity of ascites was less and the pathological type was clear cell carcinoma (45.83%) early stage of Figo stage (87.50%), the preoperative CA125 value was (1242.75 卤2104.28) U / ml, and the pathological type was serous adenocarcinoma (72.37%) late stage of Figo stage (74.71%). The difference was statistically significant (P 0.05). There was no significant difference between the two groups (P 0.05). Conclusion: the patients with malignant change of ovarian endometriosis are young in age, less in ascites, lower in CA125 before operation and earlier in Figo stage. The histopathology is mainly clear cell carcinoma and endometrial adenocarcinoma.
【作者单位】： 郑州大学人民医院;
【基金】：河南省医学科技攻关计划(No:201301007)
【分类号】：R737.31
，
本文编号：2203226
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