治疗前血清LDH和ALP与鼻咽癌预后相关性研究
发布时间：2018-09-03 12:40
【摘要】：目的:探讨治疗前血清乳酸脱氢酶(LDH)与血清碱性磷酸酶(ALP)水平对鼻咽癌患者预后的影响。方法:收集2006-04-2008-10期间在我院初治的339例鼻咽癌患者的年龄、性别、T分期、N分期、临床分期、放疗方式、放疗剂量、治疗前血清LDH水平、治疗前血清ALP水平等资料,应用单因素和多因素分析的统计学方法分析其与鼻咽癌患者预后的相关性。结果:本组病例1、3、5年生存率分别为97.8%、85.0%、78.5%,单因素分析显示年龄、临床分期、治疗前血清LDH与患者预后相关(P0.05)。多因素分析显示年龄、临床分期及治疗前血清LDH水平是影响患者预后的独立因素。结论:年龄大于50岁、Ⅲ+Ⅳ期及治疗前血清LDH升高是鼻咽癌患者复发和死亡的独立危险因素。
[Abstract]:Objective: to investigate the effect of serum lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) levels on the prognosis of nasopharyngeal carcinoma (NPC) patients before treatment. Methods: the data of age, sex T staging, clinical stage, radiotherapy method, dose of radiotherapy, serum LDH level before treatment and serum ALP level before treatment were collected in 339 patients with nasopharyngeal carcinoma treated in our hospital from April to October 2006. Univariate and multivariate analysis were used to analyze its correlation with the prognosis of nasopharyngeal carcinoma (NPC) patients. Results: the 3- and 5-year survival rates of the patients were 97.80.85% and 78.5%, respectively. Univariate analysis showed that age, clinical stage and serum LDH were correlated with the prognosis of the patients (P0.05). Multivariate analysis showed that age, clinical stage and serum LDH level before treatment were independent factors for prognosis. Conclusion: the increase of serum LDH in patients over 50 years old and in stage 鈪，
本文编号：2220006
[Abstract]:Objective: to investigate the effect of serum lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) levels on the prognosis of nasopharyngeal carcinoma (NPC) patients before treatment. Methods: the data of age, sex T staging, clinical stage, radiotherapy method, dose of radiotherapy, serum LDH level before treatment and serum ALP level before treatment were collected in 339 patients with nasopharyngeal carcinoma treated in our hospital from April to October 2006. Univariate and multivariate analysis were used to analyze its correlation with the prognosis of nasopharyngeal carcinoma (NPC) patients. Results: the 3- and 5-year survival rates of the patients were 97.80.85% and 78.5%, respectively. Univariate analysis showed that age, clinical stage and serum LDH were correlated with the prognosis of the patients (P0.05). Multivariate analysis showed that age, clinical stage and serum LDH level before treatment were independent factors for prognosis. Conclusion: the increase of serum LDH in patients over 50 years old and in stage 鈪，
本文编号：2220006
本文链接：https://www.wllwen.com/yixuelunwen/zlx/2220006.html
