网织血小板检测在急性白血病继发感染患者中的临床意义
发布时间：2018-09-10 15:12
【摘要】：目的探讨网织血小板检测在急性白血病(AL)患者继发感染时的诊断价值。方法选取189例疑似感染的AL患者,分别测定并记录其外周血白细胞计数(WBC)、中性粒细胞(N)百分比、血小板计数(PLT)、C反应蛋白(CRP)、降钙素原(PCT)、网织血小板(RP)百分比、腋下温度(T)。应用受试者工作曲线(ROC)进行诊断价值比较。采用KaplanMeier生存曲线分析RP百分比与重症感染相关的死亡率之间的关系。结果 RP百分比在诊断AL继发感染及重症感染时ROC曲线下面积明显高于其他传统炎症指标;RP百分比与CRP或PCT联合诊断感染时其灵敏度和特异度显著提高;RP百分比9.76%的重症感染组患者40 d累计生存率明显高于RP百分比≥9.76%的重症感染组患者(P0.05)。结论相较于传统炎症指标,RP百分比在诊断AL患者继发感染及重症感染时诊断价值最高,与CRP和(或)PCT联合检测有助于提高AL患者继发感染的早期诊断率。RP百分比可作为预测死亡风险的一项指标。
[Abstract]:Objective to evaluate the diagnostic value of reticulocyte in secondary infection in patients with acute leukemia (AL). Methods Peripheral blood leukocyte count (WBC), neutrophil (N) percentage, platelet count (PLT) C reactive protein (CRP), procalcitonin (PCT), reticulocyte (RP) percentage and axillary temperature (T). Were measured and recorded in 189 suspected AL patients. The diagnostic value of (ROC) was compared. KaplanMeier survival curve was used to analyze the relationship between the percentage of RP and the mortality associated with severe infection. Results the area under ROC curve in the diagnosis of AL secondary infection and severe infection in RP percentage was significantly higher than that in other traditional inflammatory markers, CRP or PCT. The sensitivity and specificity of ROC percentage were significantly higher than those of CRP or PCT in the diagnosis of infection. The cumulative survival rate of 9.76% patients with severe infection was significantly higher than that of patients with RP 鈮，
本文编号：2234814
[Abstract]:Objective to evaluate the diagnostic value of reticulocyte in secondary infection in patients with acute leukemia (AL). Methods Peripheral blood leukocyte count (WBC), neutrophil (N) percentage, platelet count (PLT) C reactive protein (CRP), procalcitonin (PCT), reticulocyte (RP) percentage and axillary temperature (T). Were measured and recorded in 189 suspected AL patients. The diagnostic value of (ROC) was compared. KaplanMeier survival curve was used to analyze the relationship between the percentage of RP and the mortality associated with severe infection. Results the area under ROC curve in the diagnosis of AL secondary infection and severe infection in RP percentage was significantly higher than that in other traditional inflammatory markers, CRP or PCT. The sensitivity and specificity of ROC percentage were significantly higher than those of CRP or PCT in the diagnosis of infection. The cumulative survival rate of 9.76% patients with severe infection was significantly higher than that of patients with RP 鈮，
本文编号：2234814
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