淋巴结转移度预测老年结直肠癌患者术后远处转移的价值

发布时间：2018-10-14 17:56

【摘要】：目的探讨淋巴结转移度(LNR)对老年结直肠癌患者术后远处转移的预测价值。方法选取2011年1月至2015年1月于该院普通外科行根治性手术的老年结直肠癌患者96例,按照有无术后远处转移将入组患者分为实验组(转移组,36例)和对照组(非转移组,60例),按照LNR水平高低将入组患者分为HLNR组和LLNR组,统计分析LNR的相关临床病理因素,单因素及多因素分析影响老年结直肠癌出现术后远处转移的临床病理因素,总结分析LNR与老年结直肠癌患者出现术后远处转移相关性。结果 HLNR组和低LLNR组在年龄、大体类型和分化程度等方面均有统计学差异(均P0.05);Logistic多因素分析结果显示,大体类型及分化程度与老年结直肠癌LNR水平独立相关(均P0.05)。实验组和对照组在大体类型、分化程度、淋巴结检出总数(ELN)及LNR等方面均有统计学差异(均P0.05),Logistic多因素分析结果显示:LNR、分化程度及大体类型与老年结直肠癌患者术后远处转移独立相关(RR:2.098;CI%:1.050~4.192;P0.05)。结论 LNR、分化程度及大体类型与老年结直肠癌术后远处转移独立相关,可联合预测老年结直肠癌术后远处转移情况。
[Abstract]:Objective to evaluate the value of lymph node metastasis (LNR) in predicting distant metastasis after operation in elderly patients with colorectal cancer. Methods from January 2011 to January 2015, 96 elderly patients with colorectal cancer underwent radical surgery in general surgery in our hospital. The patients were divided into experimental group (metastatic group, 36 cases) and control group (non-metastatic group, 60 cases) according to the distant metastasis after operation. According to the level of LNR, the patients were divided into HLNR group and LLNR group. The clinicopathological factors related to LNR were statistically analyzed. Univariate and multivariate analysis were used to analyze the clinicopathological factors influencing the distant metastasis of elderly colorectal cancer, and to summarize and analyze the correlation between LNR and postoperative distant metastasis in elderly patients with colorectal cancer. Results there were significant differences in age, gross type and differentiation between HLNR group and low LLNR group (P0.05); Logistic multivariate analysis showed that gross type and differentiation degree were independently correlated with LNR level in elderly colorectal cancer (P0.05). Experimental group and control group in gross type, differentiation degree, The total number of lymph node detected (ELN) and LNR were significantly different (P0.05), Logistic multivariate analysis results showed that the degree of LNR, differentiation and gross type of colorectal cancer patients in the elderly after the distant metastasis (RR:2.098;CI%:1.050~4.192;P0.05) was independent correlation. Conclusion the degree of differentiation and gross type of LNR, are independently correlated with distant metastasis after operation of colorectal cancer, which can be combined to predict distant metastasis after operation of colorectal cancer in elderly patients.
【作者单位】：安顺市平坝区人民医院;
【分类号】：R735.34

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