非小细胞肺癌13组、14组淋巴结转移规律探讨

发布时间：2018-11-16 10:02

【摘要】：背景与目的淋巴结转移是影响肺癌肿瘤-淋巴结-转移(tumor-node-matastasis,TNM)分期的重要因素之一,在非小细胞肺癌(non-small cell lung cancer,NSCLC)患者的手术中,13组、14组淋巴结因其隐藏于肺叶的深部而忽视做病理检测,影响术后病理分期准确性。本研究旨在探讨13组、14组淋巴结在NSCLC术中的阳性检出率及其对病理分期的影响。方法选取内蒙古医科大学附属医院100例NSCLC手术患者为研究对象,剖取胸内2组-12组、第13、14组淋巴结行病理检测,分析肿瘤的大小、部位、病理类型等因素与胸内淋巴结转移率的关系。结果 100例患者胸内淋巴结转移率为47.0%,10组-12组、N2淋巴结、13组、14组淋巴结阳性率有统计学差异(P0.05);不同T分期13组、14组淋巴结漏检率有统计学差异(P0.05);周围型与中央型NSCLC的N1期漏检率无统计学差异(P0.05);不同病理类型肿瘤之间N1期漏诊率无统计学差异(P0.05)。此外,发现有12例患者存在非肿瘤所在叶、段支气管旁淋巴结转移。结论临床上检测NSCLC 13组、14组与非肿瘤所在叶支气管旁淋巴结的转移情况十分必要,有利于获取术后准确的TNM分期,对于指导术后治疗意义重大。
[Abstract]:Background & objective lymph node metastasis is one of the important factors influencing the staging of tumor lymph node metastasis (tumor-node-matastasis,TNM) of lung cancer. In 13 groups of patients with non-small cell lung cancer (non-small cell lung cancer,NSCLC). The lymph nodes in 14 groups were neglected by pathological examination because they were hidden in the deep part of the lung lobe, which affected the accuracy of postoperative pathological staging. The purpose of this study was to investigate the positive rate of lymph nodes in 13 groups and 14 groups during NSCLC and its influence on pathological staging. Methods A total of 100 patients undergoing NSCLC operation in Inner Mongolia Medical University Hospital were selected as subjects. The lymph nodes in group 1314 were examined by pathological examination, and the size and location of the tumor were analyzed. The relationship between pathological type and intrathoracic lymph node metastasis rate. Results the positive rates of intrathoracic lymph node metastasis in 100 patients were 47.0% and 47.0% respectively. The positive rates of lymph nodes in 10 groups, N2 lymph nodes, 13 groups, 14 groups were significantly different (P0.05). In 13 groups with different T stages, there was statistical difference in the rate of lymph node leakage in 14 groups (P0.05), but there was no statistical difference between peripheral type and central type of NSCLC in N1 stage (P0.05). There was no significant difference in missed diagnosis rate between different pathological types of tumors at N1 stage (P0.05). In addition, 12 patients with non-tumor lobes and segmental parabranchial lymph node metastasis were found. Conclusion it is necessary to detect the lymph node metastasis in group NSCLC 13, group 14 and non-tumor, which is helpful to obtain accurate TNM staging after operation, and is of great significance in guiding postoperative treatment.
【作者单位】：内蒙古医科大学附属医院胸外科;
【基金】：内蒙古自治区自然科学基金项目(No.2014MS08102)资助~~
【分类号】：R734.2

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