Notch信号通路及miRNA在结直肠癌中的研究进展
发布时间：2018-11-20 04:32
【摘要】：正结直肠癌(colorectal cancer,CRC)是消化系统中最常见的恶性肿瘤之一,随着生活习惯和饮食结构的改变,结直肠癌的发病率呈逐年上升趋势,在我国及世界范围内其发病率高居恶性肿瘤的第3位~([1])。其早期缺乏特异性的临床表现,而侵袭和转移又使中晚期结直肠癌的治疗面临巨大的挑战,转移性结直肠癌的5年存活率低于20%~([2])。结直肠癌的发生、发展是涉及多个基因、多个步骤的复杂过程,但其具体机制尚不明确,因
[Abstract]:Positive colorectal cancer (colorectal cancer,CRC) is one of the most common malignant tumors in the digestive system. In our country and in the world, its incidence rate is the third highest in malignant tumor. It lacks specific clinical manifestations in the early stage, and invasion and metastasis make the treatment of advanced colorectal cancer face great challenges. The 5-year survival rate of metastatic colorectal cancer is lower than 20 ~ (2). The occurrence and development of colorectal cancer is a complex process involving multiple genes and steps, but its specific mechanism is still unclear.
【作者单位】： 遵义医学院附属医院消化内科;
【基金】：贵州省科技计划课题(黔科合SY字[2013]3006号) 贵州省科学技术基金项目(黔科合J字[2010]2172号)
【分类号】：R735.34
[Abstract]:Positive colorectal cancer (colorectal cancer,CRC) is one of the most common malignant tumors in the digestive system. In our country and in the world, its incidence rate is the third highest in malignant tumor. It lacks specific clinical manifestations in the early stage, and invasion and metastasis make the treatment of advanced colorectal cancer face great challenges. The 5-year survival rate of metastatic colorectal cancer is lower than 20 ~ (2). The occurrence and development of colorectal cancer is a complex process involving multiple genes and steps, but its specific mechanism is still unclear.
【作者单位】： 遵义医学院附属医院消化内科;
【基金】：贵州省科技计划课题(黔科合SY字[2013]3006号) 贵州省科学技术基金项目(黔科合J字[2010]2172号)
【分类号】：R735.34
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