三切口食管癌根治术后不同并发症患者感染病原菌分析

发布时间：2019-01-14 14:34

【摘要】：目的调查三切口食管癌根治术后不同并发症患者感染的病原菌分布,为临床提供参考。方法回顾性调查2014年7月-2016年10月在医院行三切口食管癌根治术后发生各类并发症的188例患者的临床资料;分析不同并发症患者术后常见病原菌的分布;使用SPSS 22.0软件进行统计分析。结果 188例患者共培养出201株病原菌,并发吻合口瘘患者检出革兰阴性菌占49.63%,革兰阳性菌占39.42%,真菌占10.95%,其中嗜麦芽寡养单胞菌检出率最高占10.95%;并发喉返神经损伤患者检出革兰阴性菌占42.48%,革兰阳性菌占34.78%,真菌占21.74%,其中白假丝酵母菌检出率最高占17.39%;肺部并发症患者检出革兰阴性菌占56.60%,革兰阳性菌占32.08%,真菌占11.32%,其中铜绿假单胞菌检出率最高占22.64%。结论三切口食管癌根治术后不同并发症患者发生院内感染后主要病原菌分布不同,可按情况使用相应敏感抗菌药物进行治疗。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria in patients with different complications after radical resection of esophageal cancer through three incisions. Methods the clinical data of 188 patients with various complications after three-incision radical resection of esophageal cancer in hospital from July 2014 to October 2016 were retrospectively investigated, and the distribution of common pathogens in patients with different complications were analyzed. SPSS 22. 0 software was used for statistical analysis. Results 201 strains of pathogenic bacteria were cultured in 188 patients. Gram-negative bacteria accounted for 49.63 in patients with anastomotic fistula, Gram-positive bacteria accounted for 39.42 and fungi accounted for 10.95. Among them, the detection rate of maltophilia oligotrophomonas was the highest. In patients with recurrent laryngeal nerve injury, Gram-negative bacteria accounted for 42.48%, Gram-positive bacteria 34.78% and fungi 21.744.The detection rate of Candida albicans was 17.39%. Gram-negative bacteria accounted for 56.60%, gram-positive bacteria 32.08 and fungi 11.3210. Among them, the highest positive rate of Pseudomonas aeruginosa was 22.644.In the patients with pulmonary complications, gram-negative bacteria accounted for 56.60%, gram-positive bacteria accounted for 32.08, fungi accounted for 11.32. Conclusion the distribution of main pathogenic bacteria in patients with different complications after radical resection of esophageal cancer through three incisions is different, and sensitive antimicrobial agents can be used according to the situation.
【作者单位】：中山大学肿瘤防治中心医院感染管理科;中山医学院临床医学系;
【分类号】：R735.1

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