术前超声癌灶特征预测甲状腺微小乳头状癌颈部中央区淋巴结转移的临床价值
发布时间：2019-02-16 08:09
【摘要】：目的 :探讨甲状腺微小乳头状癌(Papillary thyroid microcarcinoma,PTMC)术前超声癌灶特征预测颈部中央区淋巴结转移的临床价值。方法:回顾性分析2014年3月—2015年10月杭州市第一人民医院收治的182例PTMC患者的超声影像及病理资料。采用单因素和多因素Logistic回归分析术前超声癌灶特征与颈部中央区淋巴结转移的关系。结果:182例PTMC共清扫220侧中央区淋巴结,其中88侧中央区发生淋巴结转移,转移率为40.00%。单因素分析结果显示,PTMC超声癌灶特征如部位、肿瘤最大径、被膜侵犯及微钙化与其同侧中央区淋巴结转移相关(均P0.05)。多因素Logistic回归分析进一步显示,PTMC的超声癌灶特征如部位、最大径及被膜侵犯状况与其中央区淋巴结转移密切相关(均P0.05)。结论 :PTMC的癌灶超声特征如病灶部位、肿瘤最大径及被膜侵犯是术前预测中央区淋巴结转移的高危因素。
[Abstract]:Objective: to evaluate the clinical value of preoperative ultrasonographic features of thyroid micropapillary carcinoma (Papillary thyroid microcarcinoma,PTMC) in predicting lymph node metastasis in the central region of the neck. Methods: the ultrasonographic and pathological data of 182 patients with PTMC admitted to the first people's Hospital of Hangzhou from March 2014 to October 2015 were analyzed retrospectively. Univariate and multivariate Logistic regression analysis was used to analyze the relationship between the features of the foci and the lymph node metastasis in the central region of the neck. Results: one hundred and twenty two central lymph nodes were dissected in 182 patients with PTMC, 88 of them had lymph node metastasis in the central region, and the metastasis rate was 40.00. Univariate analysis showed that the location, tumor maximum diameter, membrane invasion and microcalcification were correlated with lymph node metastasis in the ipsilateral central region of PTMC (P0.05). Multivariate Logistic regression analysis further showed that the location, the maximum diameter and the invasion of the capsule were closely related to the lymph node metastasis in the central region of PTMC (P0.05). Conclusion: the ultrasonographic features of PTMC, such as the location of the tumor, the maximum diameter of the tumor and the invasion of the capsule, are the high risk factors for predicting lymph node metastasis in the central region before operation.
【作者单位】： 松阳县人民医院超声科;南京医科大学附属杭州医院(杭州市第一人民医院);杭州市肿瘤医院超声科;
【基金】：浙江省公益技术应用研究项目(2017C33180) 浙江省医药卫生科技计划项目(2015KYB293) 杭州市科技计划项目(20131813A08、20163501Y46) 杭州市医药卫生科技计划项目(2012A020、2014A02、2015A21)联合资助
【分类号】：R445.1;R736.1
本文编号：2424233
[Abstract]:Objective: to evaluate the clinical value of preoperative ultrasonographic features of thyroid micropapillary carcinoma (Papillary thyroid microcarcinoma,PTMC) in predicting lymph node metastasis in the central region of the neck. Methods: the ultrasonographic and pathological data of 182 patients with PTMC admitted to the first people's Hospital of Hangzhou from March 2014 to October 2015 were analyzed retrospectively. Univariate and multivariate Logistic regression analysis was used to analyze the relationship between the features of the foci and the lymph node metastasis in the central region of the neck. Results: one hundred and twenty two central lymph nodes were dissected in 182 patients with PTMC, 88 of them had lymph node metastasis in the central region, and the metastasis rate was 40.00. Univariate analysis showed that the location, tumor maximum diameter, membrane invasion and microcalcification were correlated with lymph node metastasis in the ipsilateral central region of PTMC (P0.05). Multivariate Logistic regression analysis further showed that the location, the maximum diameter and the invasion of the capsule were closely related to the lymph node metastasis in the central region of PTMC (P0.05). Conclusion: the ultrasonographic features of PTMC, such as the location of the tumor, the maximum diameter of the tumor and the invasion of the capsule, are the high risk factors for predicting lymph node metastasis in the central region before operation.
【作者单位】： 松阳县人民医院超声科;南京医科大学附属杭州医院(杭州市第一人民医院);杭州市肿瘤医院超声科;
【基金】：浙江省公益技术应用研究项目(2017C33180) 浙江省医药卫生科技计划项目(2015KYB293) 杭州市科技计划项目(20131813A08、20163501Y46) 杭州市医药卫生科技计划项目(2012A020、2014A02、2015A21)联合资助
【分类号】：R445.1;R736.1
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