吉林地区胃癌患者围手术期输血探讨

发布时间：2019-02-18 07:57

【摘要】：目的对于胃癌患者来说,围手术期输血(PBTs)与胃癌预后之间的关系仍有争议。本研究的目的是,探讨与本地区(吉林省)胃癌预后相关的预测影响因素,以验证PBTs对胃癌预后效果的影响。方法回顾性分析2011年1月-2015年1月,就诊于吉林大学中日联谊医院行胃癌根治术的患者173例。统计观察临床相关指标,评价各指标之间的差异因素。结果非输血病人5年生存率为77%,接受PBTs的患者(P=0.03)生存率为65%。PBTs没有给出更进一步的公认的预后类别(如依据TNM分层系统第7版的p T或p N)。包括所有已知的预后因素在内的多因素(包括癌症和非癌症相关的)分析中,没有将PBTs作为一个独立的预后因素。只是术前血红蛋白、白蛋白水平、p T和手术时间与PBTs紧密相关。结论研究显示了胃癌围手术期输血的病人会有一个较差的预后,但PBTS是一个混杂因素,而不是一个预后指标,它们明显受其他变量影响。
[Abstract]:Objective in patients with gastric cancer, the relationship between perioperative transfusion of (PBTs) and prognosis of gastric cancer remains controversial. The purpose of this study was to explore the prognostic factors related to the prognosis of gastric cancer in Jilin province and to verify the effect of PBTs on the prognosis of gastric cancer. Methods from January 2011 to January 2015, 173 patients with gastric cancer underwent radical gastrectomy in Sino-Japanese Friendship Hospital of Jilin University. Statistical observation of clinical related indicators and evaluation of the factors of difference between the indicators. Results the 5-year survival rate of non-transfusion patients was 77% and that of patients receiving PBTs (P0. 03) was that 65%.PBTs did not provide a further recognized prognostic category (e.g., according to the TNM stratification system version 7, p T or p N). PBTs is not considered as an independent prognostic factor in multivariate analysis, including all known prognostic factors, including cancer and non-cancer related factors. Only preoperative hemoglobin, albumin, p T and operative time were closely related to PBTs. Conclusion the study showed that perioperative transfusion of gastric cancer patients had a poor prognosis, but PBTS was a mixed factor, not a prognostic indicator, and they were obviously influenced by other variables.
【作者单位】：吉林省肿瘤医院胃结直肠肿瘤外二科;吉林市中心医院普通外科;吉林大学中日联谊医院新民大街分院普通外科;
【分类号】：R735.2

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