内镜治疗肝癌合并门静脉癌栓引起的食管胃底静脉曲张出血的疗效分析

发布时间：2019-03-01 14:19

【摘要】：目的明确内镜治疗肝癌合并门静脉癌栓患者发生食管胃底静脉曲张出血的止血效果与意义。方法回顾性分析2013年1月-2015年12月首都医科大学附属北京地坛医院住院收治食管胃底静脉曲张出血的肝癌伴门静脉癌栓的患者,比较非内镜治疗组和内镜治疗组患者止血治疗效果、主要死亡原因及生存时间。结果共纳入76例患者,非内镜治疗组27例,内镜治疗组49例。非内镜治疗组有40.7%(11/27)的患者1周内死亡,81.5%(22/27)死于食管胃底静脉曲张出血,平均生存期为(42.03±13.94)d;内镜治疗组仅16.3%(8/49)的患者1周内死亡(P0.05),55.1%(27/49)死于食管胃底静脉曲张出血(P0.05),平均生存期为(174.24±34.42)d(P0.05)。结论内镜下治疗能有效地降低患者死于食管胃底静脉曲张出血的风险,延长患者生存期,具有临床意义。
[Abstract]:Objective to determine the hemostatic effect and significance of endoscopic treatment of esophageal and gastric variceal bleeding in patients with hepatocellular carcinoma complicated with portal vein tumor thrombus. Methods from January 2013 to December 2015, the patients with hepatocellular carcinoma complicated with portal vein tumor thrombus who were admitted to The Temple of Earth Hospital of Beijing, affiliated to Capital Medical University, were retrospectively analyzed, who suffered from esophageal and gastric variceal bleeding. To compare the hemostatic effect, main cause of death and survival time between non-endoscopic treatment group and endoscopic treatment group. Results 76 patients were divided into non-endoscopic group (n = 27) and endoscopic group (n = 49). In the non-endoscopic treatment group, 40.7% (11 / 27) patients died within one week, and 81.5% (22 / 27) died of esophageal and gastric varices bleeding. The mean survival time was (42.03 卤13.94) days. In the endoscopic treatment group, only 16.3% (8 / 49) patients died within one week (P0.05), 55.1% (27 / 49) died of esophageal and gastric varices bleeding (P0.05), and the mean survival time was (174.24 卤34.42) d (P0.05). Conclusion Endoscopic therapy can effectively reduce the risk of death from esophageal and gastric varices bleeding and prolong the survival time of the patients.
【作者单位】：北京市垂杨柳医院消化科;首都医科大学附属北京地坛医院消化科;
【分类号】：R735.7

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