婴儿血管瘤及血管畸形临床分析
发布时间：2019-03-03 16:59
【摘要】：目的通过对大样本婴儿血管瘤及血管畸形相关临床资料进行详细统计分析,结合该类疾病相关文献,掌握婴儿血管瘤及血管畸形的发生、演变特点,指导该类疾病的临床诊治。研究对象及方法研究对象:2014年9月-2016年9月重庆医科大学附属儿童医院血管瘤专科门诊接诊的2563例婴儿血管瘤及血管畸形患者。研究方法:设计婴儿血管瘤及血管畸形统计表,对首次就诊时确诊为婴儿血管瘤及血管畸形患者相关临床资料,包括患者性别、发病及就诊年龄、病变分类、大小分型、病变部位、生长情况、相关并发症、是否早产、家庭住址等按所设计的统计表进行详细记录,利用spss17.0统计软件统计,分析各项资料的构成百分比及相互之间的关系。结果2150例婴儿血管瘤,血管瘤2450个,女性患儿1436例,男性患儿714例,男女发病比例为1:2;血管畸形女性患儿220例,男性患儿193例,比例为1.12:1;婴儿血管瘤出生时即出现病变者1206个,占41.9%,1月内出现者1944个,占79.35%,3月以上出现病变患儿71个,仅占2.9%;1853个于半岁内就诊,占75.7%,1岁以上首次就诊者103个,占4.2%;血管畸形首次就诊年龄无明显特点,各年龄段均有就诊;婴儿血管瘤病变类型以表浅型血管瘤为主,1740个,占70.8%;血管畸形则以静脉畸形为主,209个,占49.9%;婴儿血管瘤发病部位以头面颈及躯干为主,分别为1072个及760个,占43.8%和31.0%;血管畸形头面颈发病率最高,共201个,占48.7%;婴儿血管瘤首次就诊时病变大小主要以中小型为主,2308个,占94%,大型及巨大型142个,仅占6%;血管畸形中小型284个,占68.5%,大型及巨大型130个,占31.5%;婴儿血管瘤首次就诊时1958个处于生长期,占79.92%,390个处于稳定期,占15.92%,102个处于消退期,占4.19%;婴儿血管瘤多发234例,占11%,血管畸形多发患儿仅3例;婴儿血管瘤早产儿109例,占5%,血管畸形早产儿仅23例。结论婴儿血管瘤男女发病率有显著差异,发生、生长均具有明显特点,可自行消退,就诊年龄亦具有相应特点,治疗上可根据具体情况进行选择;血管畸形生后即存在,生长缓慢,部分患儿就诊较晚,导致病变较大,增加了治疗难度;故在治疗上建议早期进行干预。
[Abstract]:Objective to analyze the clinical data of large samples of infantile hemangioma and vascular malformations, and to understand the occurrence and evolution characteristics of hemangioma and vascular malformations in infants, so as to guide the clinical diagnosis and treatment of these diseases. Participants and methods: from September 2014 to September 2016, 2563 cases of infantile hemangioma and vascular malformations were treated in the out-patient clinic of hemangioma, affiliated Children's Hospital of Chongqing Medical University. Methods: to design the statistical tables of hemangioma and vascular malformation in infants, and to analyze the clinical data of the patients diagnosed as hemangioma and vascular malformation at the first visit, including the sex of the patient, the onset and age of the patient, the classification of the lesion, and the classification of the size of the disease. The lesion site, growth condition, related complications, preterm birth, family address and so on were recorded in detail according to the designed statistical tables, and the percentage of each data and the relationship between them were analyzed by using spss17.0 statistical software. Results 2150 cases of infantile hemangioma, 2450 hemangioma, 1436 female and 714 male, the ratio of male to female was 1-2, the ratio of female to male was 1.12%, the ratio of female to female was 1.12%, and the ratio of female to male was 1.12%. There were 1206 cases (41.9%) of hemangioma at birth, 1944 cases (79.35%) occurred within 1 month, 71 cases (2.9%) appeared more than 3 months after birth. 1853 patients (75.7%) were in the first visit within the age of half year, and over one year old (4.2%), there was no significant difference in the age of the first visit of vascular malformations, and all the age groups were found to be in the first visit. The main types of hemangioma in infants were superficial hemangiomas (1740, 70.8%), venous malformations (49.9%), venous malformations (70.8%) and venous malformations (49.9%). The main sites of infantile hemangioma were head, face, neck and torso, accounting for 43.8% and 31.0%, respectively, and the incidence of vascular malformations was the highest (48.7%, 48.7%), and the incidence of vascular malformations was the highest (48.7%). The size of hemangioma in infants was mainly small and medium size (94%), large and giant (6%), vascular malformations (68.5%), large and giant (31.5%), small and medium size (68.5%), large and giant (31.5%), small and medium size (68.5%), large and giant (31.5%). 1958 hemangiomas were in the growth phase (79.92%), stable phase (15.92%) and receding stage (4.19%). There were 234 cases (11%) with multiple hemangiomas, 3 cases with multiple vascular malformations, 109 cases (5%) with hemangioma and 23 cases with vascular malformations. Conclusion there is a significant difference in the incidence of hemangioma between males and females. The growth of hemangioma is characterized by its own regression and age of treatment. The treatment can be selected according to the specific conditions. Vascular malformations exist immediately after birth, grow slowly, and some children come to hospital later, which leads to large pathological changes and increases the difficulty of treatment. Therefore, early intervention is recommended in the treatment of vascular malformations.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R732.2
本文编号：2433913
[Abstract]:Objective to analyze the clinical data of large samples of infantile hemangioma and vascular malformations, and to understand the occurrence and evolution characteristics of hemangioma and vascular malformations in infants, so as to guide the clinical diagnosis and treatment of these diseases. Participants and methods: from September 2014 to September 2016, 2563 cases of infantile hemangioma and vascular malformations were treated in the out-patient clinic of hemangioma, affiliated Children's Hospital of Chongqing Medical University. Methods: to design the statistical tables of hemangioma and vascular malformation in infants, and to analyze the clinical data of the patients diagnosed as hemangioma and vascular malformation at the first visit, including the sex of the patient, the onset and age of the patient, the classification of the lesion, and the classification of the size of the disease. The lesion site, growth condition, related complications, preterm birth, family address and so on were recorded in detail according to the designed statistical tables, and the percentage of each data and the relationship between them were analyzed by using spss17.0 statistical software. Results 2150 cases of infantile hemangioma, 2450 hemangioma, 1436 female and 714 male, the ratio of male to female was 1-2, the ratio of female to male was 1.12%, the ratio of female to female was 1.12%, and the ratio of female to male was 1.12%. There were 1206 cases (41.9%) of hemangioma at birth, 1944 cases (79.35%) occurred within 1 month, 71 cases (2.9%) appeared more than 3 months after birth. 1853 patients (75.7%) were in the first visit within the age of half year, and over one year old (4.2%), there was no significant difference in the age of the first visit of vascular malformations, and all the age groups were found to be in the first visit. The main types of hemangioma in infants were superficial hemangiomas (1740, 70.8%), venous malformations (49.9%), venous malformations (70.8%) and venous malformations (49.9%). The main sites of infantile hemangioma were head, face, neck and torso, accounting for 43.8% and 31.0%, respectively, and the incidence of vascular malformations was the highest (48.7%, 48.7%), and the incidence of vascular malformations was the highest (48.7%). The size of hemangioma in infants was mainly small and medium size (94%), large and giant (6%), vascular malformations (68.5%), large and giant (31.5%), small and medium size (68.5%), large and giant (31.5%), small and medium size (68.5%), large and giant (31.5%). 1958 hemangiomas were in the growth phase (79.92%), stable phase (15.92%) and receding stage (4.19%). There were 234 cases (11%) with multiple hemangiomas, 3 cases with multiple vascular malformations, 109 cases (5%) with hemangioma and 23 cases with vascular malformations. Conclusion there is a significant difference in the incidence of hemangioma between males and females. The growth of hemangioma is characterized by its own regression and age of treatment. The treatment can be selected according to the specific conditions. Vascular malformations exist immediately after birth, grow slowly, and some children come to hospital later, which leads to large pathological changes and increases the difficulty of treatment. Therefore, early intervention is recommended in the treatment of vascular malformations.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R732.2
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