经气管镜超声引导针吸活检与支气管镜针吸活检技术在纵隔及肺门占位性疾病诊断中的应用和比较
发布时间：2019-03-25 19:17
【摘要】：目的评价经气管镜超声引导针吸活检(EBUS-TBNA)与常规经支气管镜针吸活检(C-TBNA)在纵隔及肺门占位性疾病诊断中的价值。方法收集2010年-2016年新医大一附院纵隔、肺门占位性疾病患者301例,其中行C-TBNA检查者183例,行EBUS-TBNA检查者118例,比较两种方法穿刺阳性率及并发症情况,探究EBUS-TBNA技术的价值及优势所在。结果 (1)EBUS-TBNA患者的中央区组淋巴结(2R、4L、4R、7)活检阳性率高于周围区组淋巴结(10R、10L、11R、11L)(P0.05),EBUS-TBNA于2R、4R、7组淋巴结活检阳性率高于C-TBNA组,差异具有统计学意义(P0.05);(2)EBUS-TBNA于4R和7组淋巴结穿刺的一针阳性率明显高于C-TBNA组(P0.05),三针累计阳性率基本接近该穿刺部位总体阳性率(P0.05),可获得较满意穿刺效果;(3)EBUS-TBNA组诊断技术的准确度及敏感度优于C-TBNA组(P0.05),尤其对纵隔、肺门良性疾病的检出率高于C-TBNA组(P0.05);(4)两组患者并发症的发生率无明显差异(P0.05)。结论 EBUS-TBNA对不明原因纵隔、肺门占位或气管、支气管腔外病变的诊断具有重要价值,是一种安全、有效的操作技术。
[Abstract]:Objective to evaluate the value of transtracheal ultrasound guided needle aspiration biopsy (EBUS-TBNA) and conventional transbronchial needle aspiration biopsy (C-TBNA) in the diagnosis of mediastinal and hilar space occupying diseases. Methods from 2010 to 2016, 301 patients with mediastinal and hilar space-occupying diseases in the first affiliated Hospital of New Medical University were collected. Among them, 183 cases underwent C-TBNA examination and 118 cases underwent EBUS-TBNA examination. The positive rates and complications of puncture were compared between the two methods. Explore the value and advantages of EBUS-TBNA technology. Results (1) the positive rate of biopsy in the central lymph nodes (2R, 4L, 4R, 7) of the patients with EBUS-TBNA was higher than that in the peripheral lymph nodes (10R, 10L, 11R, 11L) (P0.05), and the EBUS-TBNA was 2R, 4R. The positive rate of lymph node biopsy in 7 groups was significantly higher than that in C-TBNA group (P0.05). (2) the positive rate of EBUS-TBNA in 4R and 7 groups was significantly higher than that in C-TBNA group (P0.05), and the cumulative positive rate of three needles was close to the overall positive rate of the puncture site (P0.05). (3) the diagnostic accuracy and sensitivity of EBUS-TBNA group was better than that of C-TBNA group (P0.05), especially for mediastinal and hilar benign diseases, the detection rate of benign disease was higher than that of C-TBNA group (P0.05). (4) there was no significant difference in the incidence of complications between the two groups (P0.05). Conclusion EBUS-TBNA is a safe and effective technique for the diagnosis of unknown mediastinal, hilar space occupying, tracheobronchial and extrabronchial lesions.
【作者单位】： 新疆医科大学一附院呼吸科;新疆医科大学一附院老年病科;
【基金】：新疆维吾尔自治区自然科学基金(No:2015211C049)
【分类号】：R56;R734
本文编号：2447242
[Abstract]:Objective to evaluate the value of transtracheal ultrasound guided needle aspiration biopsy (EBUS-TBNA) and conventional transbronchial needle aspiration biopsy (C-TBNA) in the diagnosis of mediastinal and hilar space occupying diseases. Methods from 2010 to 2016, 301 patients with mediastinal and hilar space-occupying diseases in the first affiliated Hospital of New Medical University were collected. Among them, 183 cases underwent C-TBNA examination and 118 cases underwent EBUS-TBNA examination. The positive rates and complications of puncture were compared between the two methods. Explore the value and advantages of EBUS-TBNA technology. Results (1) the positive rate of biopsy in the central lymph nodes (2R, 4L, 4R, 7) of the patients with EBUS-TBNA was higher than that in the peripheral lymph nodes (10R, 10L, 11R, 11L) (P0.05), and the EBUS-TBNA was 2R, 4R. The positive rate of lymph node biopsy in 7 groups was significantly higher than that in C-TBNA group (P0.05). (2) the positive rate of EBUS-TBNA in 4R and 7 groups was significantly higher than that in C-TBNA group (P0.05), and the cumulative positive rate of three needles was close to the overall positive rate of the puncture site (P0.05). (3) the diagnostic accuracy and sensitivity of EBUS-TBNA group was better than that of C-TBNA group (P0.05), especially for mediastinal and hilar benign diseases, the detection rate of benign disease was higher than that of C-TBNA group (P0.05). (4) there was no significant difference in the incidence of complications between the two groups (P0.05). Conclusion EBUS-TBNA is a safe and effective technique for the diagnosis of unknown mediastinal, hilar space occupying, tracheobronchial and extrabronchial lesions.
【作者单位】： 新疆医科大学一附院呼吸科;新疆医科大学一附院老年病科;
【基金】：新疆维吾尔自治区自然科学基金(No:2015211C049)
【分类号】：R56;R734
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