肾脏恶性孤立性纤维肿瘤（1例报告并文献复习）

发布时间：2019-03-30 22:32

【摘要】：目的:探讨肾脏恶性孤立性纤维肿瘤(Malignant solitary fibroustumor,MSFT)的临床表现、影像学特点、诊断与鉴别诊断、治疗及预后。方法:回顾性分析1例罕见的肾恶性SFT患者的临床资料,结合相关文献分析该病的组织来源、病理学特征、鉴别诊断及治疗随访情况。结果:29岁男性患者1例,术前诊断为右肾透明细胞癌,行后腹腔镜下根治性肾切除术,术后病理为右肾低度恶性SFT,免疫组化提示CD34(+)、BCL-2(+)、CD68(+)、CD99(+)、vimentin(+)、Ki 67 5%(+)、SMA局灶弱阳性。随访4月,未见肿瘤复发或转移。结论:肾脏恶性SFT非常罕见,诊断与鉴别诊断依据术后病理学及免疫组化学,主要治疗方式为根治性肾切除术,预后较好。
[Abstract]:Objective: to investigate the clinical manifestations, imaging features, diagnosis and differential diagnosis, treatment and prognosis of renal malignant solitary fibrous tumor (Malignant solitary fibroustumor,MSFT). Methods: the clinical data of a rare case of renal malignant SFT were retrospectively analyzed. The histological origin, pathological features, differential diagnosis and therapeutic follow-up of the disease were analyzed. Results: a 29-year-old male patient was diagnosed as right renal clear cell carcinoma before operation. Retroperitoneal laparoscopic radical nephrectomy was performed. Postoperative pathology was low grade malignant SFT, immunohistochemical diagnosis of right kidney. CD34 (), BCL-2 (), CD68 (), was suggested by immunohistochemistry. CD99 (), vimentin (), Ki 67.5% (), SMA was weakly positive. Follow-up for 4 months showed no recurrence or metastasis of the tumor. Conclusion: renal malignant SFT is very rare. The diagnosis and differential diagnosis are based on postoperative pathology and immuno-histochemistry. The main treatment is radical nephrectomy with a good prognosis.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.11

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