宫颈癌患者生殖道细菌感染及人乳头瘤病毒感染情况分析
发布时间：2019-03-31 11:34
【摘要】：目的对宫颈癌患者生殖道细菌感染及人乳头瘤病毒(HPV)感染情况进行研究,探讨宫颈癌和生殖道细菌感染及人乳头瘤病毒感染的关系。方法选择2012年1月-2014年12月湖州市中心医院妇产科宫颈癌患者108例作为宫颈癌组,慢性宫颈炎患者108例作为宫颈炎组,对两组患者阴道分泌物进行细菌培养,并检测HPV感染情况。结果 108例宫颈癌患者检出细菌60例,检出率为55.6%,108例慢性宫颈炎患者中检出细菌53例,检出率为49.1%;宫颈癌组和宫颈炎组患者生殖道细菌培养阳性率比较差异无统计学意义;宫颈癌组和宫颈炎组患者生殖道革兰阳性菌和革兰阴性菌分布比较差异无统计学意义;108例宫颈癌患者中生殖道HPV感染65例,感染率60.2%,108例慢性宫颈炎患者生殖道HPV感染44例,感染率40.7%;宫颈癌组患者生殖道HPV阳性率高于宫颈炎组(P0.05);宫颈癌患者中HPV阳性组和HPV阴性组生殖道细菌培养结果比较差异无统计学意义;宫颈癌组和宫颈炎组HPV阳性患者中生殖道细菌培养结果比较差异无统计学意义。结论生殖道HPV感染为宫颈癌的高危因素,生殖道细菌感染可能和宫颈癌的发生无关。
[Abstract]:Aim to investigate the relationship between bacterial infection of cervical cancer and reproductive tract and human papillomavirus (HPV) infection by studying the bacterial infection of reproductive tract and (HPV) infection of human papillomavirus (HPV) in cervical cancer patients. Methods 108 cervical cancer patients in Huzhou Central Hospital from January 2012 to December 2014 were selected as cervical cancer group and 108 chronic cervicitis patients as cervicitis group. HPV infection was detected. Results bacteria were detected in 60 cases (55.6%) of 108 cases of cervical cancer and 53 cases (49.1%) of 108 cases of chronic cervicitis. There was no significant difference between cervical cancer group and cervicitis group in the positive rate of germ culture, but there was no significant difference between cervical cancer group and cervicitis group in the distribution of Gram-positive bacteria and Gram-negative bacteria in the reproductive tract of cervical cancer group and cervicitis group. The infection rate of HPV was 60.2% in 65 cases of cervical cancer, and 40.7% in 44 cases of chronic cervicitis, the positive rate of HPV in cervical cancer group was higher than that in cervicitis group (P0.05), and the positive rate of HPV in cervical cancer group was higher than that in cervicitis group (P0.05). There was no significant difference between HPV-positive group and HPV-negative group in bacterial culture of genital tract between cervical cancer group and cervicitis group, but there was no significant difference between cervical cancer group and cervicitis group in HPV-positive group. Conclusion HPV infection in reproductive tract is a high risk factor of cervical cancer, and bacterial infection in reproductive tract may not be related to the occurrence of cervical cancer.
【作者单位】： 湖州市中心医院妇产科;湖州市妇幼保健院产前诊断中心;
【基金】：浙江省医药卫生一般研究计划项目(2014KYA208)
【分类号】：R737.33
本文编号：2450864
[Abstract]:Aim to investigate the relationship between bacterial infection of cervical cancer and reproductive tract and human papillomavirus (HPV) infection by studying the bacterial infection of reproductive tract and (HPV) infection of human papillomavirus (HPV) in cervical cancer patients. Methods 108 cervical cancer patients in Huzhou Central Hospital from January 2012 to December 2014 were selected as cervical cancer group and 108 chronic cervicitis patients as cervicitis group. HPV infection was detected. Results bacteria were detected in 60 cases (55.6%) of 108 cases of cervical cancer and 53 cases (49.1%) of 108 cases of chronic cervicitis. There was no significant difference between cervical cancer group and cervicitis group in the positive rate of germ culture, but there was no significant difference between cervical cancer group and cervicitis group in the distribution of Gram-positive bacteria and Gram-negative bacteria in the reproductive tract of cervical cancer group and cervicitis group. The infection rate of HPV was 60.2% in 65 cases of cervical cancer, and 40.7% in 44 cases of chronic cervicitis, the positive rate of HPV in cervical cancer group was higher than that in cervicitis group (P0.05), and the positive rate of HPV in cervical cancer group was higher than that in cervicitis group (P0.05). There was no significant difference between HPV-positive group and HPV-negative group in bacterial culture of genital tract between cervical cancer group and cervicitis group, but there was no significant difference between cervical cancer group and cervicitis group in HPV-positive group. Conclusion HPV infection in reproductive tract is a high risk factor of cervical cancer, and bacterial infection in reproductive tract may not be related to the occurrence of cervical cancer.
【作者单位】： 湖州市中心医院妇产科;湖州市妇幼保健院产前诊断中心;
【基金】：浙江省医药卫生一般研究计划项目(2014KYA208)
【分类号】：R737.33
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