胆囊癌预后的多因素分析
发布时间:2019-05-15 14:07
【摘要】:目的:探究胆囊癌病理分期及手术方式对胆囊癌预后的因素。材料与方法:回顾性分析吉林大学附属第二医院2010年—2015年手术并经病理证实为胆囊癌的患者59例。术后病理所有病理均证实为胆囊癌,按Nevin分期,Ⅰ期2例,Ⅱ期12例,Ⅲ期22例,Ⅳ期12例,Ⅴ期11例。单纯胆囊切除19人,胆囊癌根治术28人,姑息性手术12人。采用采用Kaplan-Meier法和Log-rank法对其病理分期、手术方法与预后的关系进行统计分析,研究各病理分期、手术方式不同对胆囊癌患者生存期的影响。结果:本组研究59个病例,48例获得随访,随访率为81.4%。总体生存时间为9个月。Ⅰ+Ⅱ期、Ⅲ+Ⅳ期、Ⅴ期三组中位生存时间分别为30个月、14个月和3个月。Ⅰ+Ⅱ期、Ⅲ+Ⅳ期胆囊癌患者生存率高于Ⅴ期胆囊癌患者,差异均有统计学意义(P0.05);Ⅰ+Ⅱ期胆囊癌患者生存率高于Ⅲ+Ⅳ期,差异有统计学意义(P0.05)。胆囊癌根治术、单纯胆囊切除术及姑息性手术切除术组的中位生存期分别为:15个月、9个月、4个月。单纯胆囊切除组和根治性手术组患者生存率均高于姑息性手术组患者,胆囊癌根治组生存率高于单纯胆囊切除组,差异具有统计学意义(P0.05)。结论:胆囊癌的病理分期越早其预后越好。依病理分期选择相应术式,胆囊癌根治术和单纯胆囊切除术效果优于姑息性手术治疗,胆囊癌根治术效果优于单纯胆囊癌根治术。
[Abstract]:Objective: To study the pathological staging of gallbladder carcinoma and the factors affecting the prognosis of gallbladder carcinoma. Materials and Methods:59 patients with gallbladder carcinoma were retrospectively analyzed in the second hospital in Jilin University in 2010. All the pathology of the post-operative pathology proved to be the gallbladder carcinoma. According to the Nevin stage, the stage I was 2 cases, the second stage was 12 cases, the stage 鈪,
本文编号:2477561
[Abstract]:Objective: To study the pathological staging of gallbladder carcinoma and the factors affecting the prognosis of gallbladder carcinoma. Materials and Methods:59 patients with gallbladder carcinoma were retrospectively analyzed in the second hospital in Jilin University in 2010. All the pathology of the post-operative pathology proved to be the gallbladder carcinoma. According to the Nevin stage, the stage I was 2 cases, the second stage was 12 cases, the stage 鈪,
本文编号:2477561
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