DWI对直肠黏液腺癌与非黏液腺癌的鉴别诊断价值

发布时间：2019-05-17 07:44

【摘要】：目的:探讨磁共振扩散加权成像(DWI)及其表观扩散系数(ADC)值对直肠黏液腺癌与非黏液腺癌的鉴别诊断价值。方法:回顾性分析经手术病理证实的16例直肠黏液腺癌与64例非黏液腺癌患者的MR资料,观察所有肿瘤的DWI信号强度,测量肿瘤ADC值及相对ADC(rADC)值,并绘制受试者工作特性(ROC)曲线,计算ADC值及rADC值对直肠黏液腺癌与非黏液腺癌的鉴别诊断效能。结果:16例直肠黏液腺癌中4例在DWI图像上呈低号,12例呈高信号,64例非黏液腺癌中1例呈低信号,63例呈高信号,两者DWI信号强度差异有统计学意义(χ2=8.333,P=0.004)。黏液腺癌的ADC值[(1.48±0.25)×10-3 mm2/s]及rADC值(1.22±0.18)均高于非黏液腺癌[(1.08±0.11)×10-3 mm2/s,(0.95±0.11)],差异均具有统计学意义(t=6.162,P0.001;t=5.810,P0.001)。以ADC值=1.209×10-3 mm2/s鉴别诊断黏液腺癌与非黏液腺癌的效能最高(AUC 0.923,敏感度93.8%,特异度89.1%)。结论:DWI及ADC值在直肠黏液腺癌与非黏液腺癌的鉴别诊断中具有重要价值。
[Abstract]:Objective: to evaluate the value of magnetic resonance diffusion weighted imaging (DWI) and its apparent diffusion coefficient (ADC) in the differential diagnosis of rectal mucinous carcinoma and non-mucinous carcinoma. Methods: the MR data of 16 cases of rectal mucinous carcinoma and 64 cases of non-mucinous carcinoma confirmed by operation and pathology were analyzed retrospectively. the DWI signal intensity, ADC value and relative ADC (rADC) value of all tumors were observed. The (ROC) curve of working characteristics of the subjects was drawn, and the differential diagnosis efficiency of ADC value and RADC value between rectal mucinous carcinoma and non-mucinous carcinoma was calculated. Results: among 16 cases of rectal mucinous carcinoma, 4 cases showed low signal intensity on DWI images, 12 cases showed high signal intensity, 1 case showed low signal intensity and 63 cases showed high signal intensity in 64 cases of non-mucinous adenocarcinoma. There was significant difference in DWI signal intensity between the two groups (蠂 ~ 2 鈮，

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