单孔与多孔VATS肺癌切除术后慢性疼痛及生活质量的对比研究
发布时间：2019-06-01 19:48
【摘要】：目的:比较单孔与多孔VATS治疗早期非小细胞肺癌两种手术方式对术后患者慢性疼痛及生活质量的影响,探讨单孔VATS在早期肺癌治疗中的应用前景。研究方法:收集青岛大学医学院附属医院胸外科自2016年4月-2017年4月接受肺癌根治术的100例患者的临床资料,其中行单孔胸腔镜(单孔组)50例,其中男28例,女22例,年龄(58.8±7.3)岁,多孔胸腔镜(多孔组)50例,其中男31例,女19例,年龄(60.4±8.1)岁,两组患者均行肺叶切除及系统性淋巴结清扫术,术后病理诊断为ⅠA-ⅠB期的非小细胞肺癌。对比两组的临床资料,以数字评分量表(Numerical Rating Scale,NRS)评估两组患者术后3月及6月的疼痛情况。应用由欧洲癌症研究与治疗组织(European Organization for Research and Treatment,EORTC)开发的生活质量核心问卷量表(Quality of Life-Core 30 Questionnaire,QLQ-C30)评估两组患者术前、术后第3个月及6个月的生活质量。研究结果:两组患者在年龄、性别、肿瘤所在肺叶、肿瘤病理分期、病理类型、手术时间、术中出血量、术后并发症、拔管时间等方面差异无统计学意义(P0.05),单孔组术后3个月及6个月NRS评分[(2.12±1.05),(1.05±0.92)]与多孔组[(2.35±1.21),(1.38±0.45)]相当(P0.05),结果表明两组患者在术后3月及术后6月的疼痛程度相当,且两组术后6月疼痛程度均低于术后3月,QLQ-C30评分显示两组患者术后3月功能领域中的情绪功能方面单孔VATS组(70.2±9.3)优于多孔VATS组(59.6±8.7)(P0.05),差异有统计学意义,两组患者术后6月的各项QLQ-C30评分相当(P0.05),较术后3月均有所提高,并接近术前水平,评分结果表明单孔组术后3月生存质量高于多孔组,术后6月两组生活质量相当,基本恢复至术前水平。结论:1.单孔VATS与多孔VATS对于早期非小细胞肺癌的治疗同样安全可靠,能够达到相同的手术效果2.接受单孔VATS肺癌切除术患者术后3月生存质量优于多孔VATS,术后6月两组均恢复至接近术前水平。相比多孔VATS组,单孔VATS组患者在术后6月内生存质量存在优势。3.单孔VATS组肺癌切除术安全可靠,疗效肯定,创伤更小,术后恢复更快,在肺癌的外科治疗中具有广阔的应用前景。
[Abstract]:Objective: to compare the effects of single pore and porous VATS on chronic pain and quality of life in patients with early non-small cell lung cancer (NSCLC), and to explore the application prospect of single pore VATS in the treatment of early lung cancer. Methods: the clinical data of 100 patients undergoing radical resection of lung cancer in the affiliated Hospital of Medical College of Qingdao University from April 2016 to April 2017 were collected. Among them, 50 patients underwent single hole thoracoscopy (single hole group), including 28 males and 22 females. The age was (58.8 卤7.3) years old. There were 50 cases of porous thoracoscopy (porous group), including 31 males and 19 females, aged (60.4 卤8.1) years. Postoperative pathological diagnosis was stage 鈪，
本文编号：2490533
[Abstract]:Objective: to compare the effects of single pore and porous VATS on chronic pain and quality of life in patients with early non-small cell lung cancer (NSCLC), and to explore the application prospect of single pore VATS in the treatment of early lung cancer. Methods: the clinical data of 100 patients undergoing radical resection of lung cancer in the affiliated Hospital of Medical College of Qingdao University from April 2016 to April 2017 were collected. Among them, 50 patients underwent single hole thoracoscopy (single hole group), including 28 males and 22 females. The age was (58.8 卤7.3) years old. There were 50 cases of porous thoracoscopy (porous group), including 31 males and 19 females, aged (60.4 卤8.1) years. Postoperative pathological diagnosis was stage 鈪，
本文编号：2490533
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