原发性气管支气管淋巴瘤两例报告并文献复习
发布时间：2019-06-13 12:23
【摘要】：目的提高对原发性气管支气管淋巴瘤的认识。方法回顾性分析本院2013年和2015年收治的2例原发性气管支气管淋巴瘤患者的临床资料并进行相关文献复习。以"气管淋巴瘤"或"支气管淋巴瘤"为检索词检索中国期刊网全文数据库、万方数据库及维普数据库,以"Trachea"OR"Bronchus"AND"Lymphoma"为检索词检索Pub Med、Ovid Medline及Embase数据库,共检索到72例原发于初级支气管,并没有胸腔外淋巴瘤依据的原发性气管支气管淋巴瘤。对患者的临床、影像学、病理组织学特点、治疗及预后进行总结。结果本院收治的2例原发性气管支气管淋巴瘤患者均为女性,以"咳嗽、呼吸困难"为主诉就诊,经纤维支气管镜活检诊断为B细胞淋巴瘤1例,套细胞淋巴瘤1例。经化疗后,患者症状明显缓解,随访至2016年10月病情未复发。文献复习发现原发气管支气管淋巴瘤病发病年龄为16~82岁,中位年龄51岁,也可见于年轻人,发病年龄16~30岁9例(12.50%);女性居多(47例,占65.28%)。主要症状为呼吸困难和咳嗽,肺功能提示阻塞性通气功能障碍,胸部CT可见气管或支气管内结节影伴或不伴肺不张,支气管镜下可见肿物,病理类型以黏膜相关淋巴组织(MALT)淋巴瘤最常见(36.11%)。套细胞淋巴瘤目前尚未见报道。结论原发性气管支气管淋巴瘤是较少见的气管肿瘤之一,其临床表现、影像学和支气管镜下表现并无特异性,易与肺癌混淆,可出现危及生命的呼吸道梗阻。支气管镜检查对该病诊断有较大价值,确诊需依赖组织病理学检查。最常见病理类型为MALT淋巴瘤,其预后较好。
[Abstract]:Objective to improve the understanding of primary tracheobronchial lymphoma. Methods the clinical data of 2 patients with primary tracheobronchial lymphoma treated in our hospital in 2013 and 2015 were analyzed retrospectively and the related literature was reviewed. The full-text database of Chinese journal network, Wanfang database and VIP database were searched with "trachea OR" or "bronchial lymphoma" as search words, and "Trachea" OR "Bronchus" AND "Lymphoma" were used as search words to search Pub Med,Ovid Medline and Embase databases. A total of 72 cases of primary tracheobronchial lymphomas with primary bronchus originated in primary bronchus and no extrathoracic lymphomas were searched. The clinical, imaging, pathological characteristics, treatment and prognosis of the patients were summarized. Results two cases of primary tracheobronchial lymphomas were treated in our hospital. "cough, dyspnea" were the main complaints. 1 case of B-cell lymphomas and 1 case of sleeve-cell lymphomas were diagnosed by fiberoptic bronchoscopy. After chemotherapy, the symptoms of the patients were significantly relieved and no recurrence was found until October 2016. Literature review showed that the age of primary tracheobronchial lymphomatosis was 16 鈮，
本文编号：2498525
[Abstract]:Objective to improve the understanding of primary tracheobronchial lymphoma. Methods the clinical data of 2 patients with primary tracheobronchial lymphoma treated in our hospital in 2013 and 2015 were analyzed retrospectively and the related literature was reviewed. The full-text database of Chinese journal network, Wanfang database and VIP database were searched with "trachea OR" or "bronchial lymphoma" as search words, and "Trachea" OR "Bronchus" AND "Lymphoma" were used as search words to search Pub Med,Ovid Medline and Embase databases. A total of 72 cases of primary tracheobronchial lymphomas with primary bronchus originated in primary bronchus and no extrathoracic lymphomas were searched. The clinical, imaging, pathological characteristics, treatment and prognosis of the patients were summarized. Results two cases of primary tracheobronchial lymphomas were treated in our hospital. "cough, dyspnea" were the main complaints. 1 case of B-cell lymphomas and 1 case of sleeve-cell lymphomas were diagnosed by fiberoptic bronchoscopy. After chemotherapy, the symptoms of the patients were significantly relieved and no recurrence was found until October 2016. Literature review showed that the age of primary tracheobronchial lymphomatosis was 16 鈮，
本文编号：2498525
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