氩氦冷冻消融术前外周血中性粒细胞与淋巴细胞比值对原发性肝癌患者预后的影响
发布时间：2019-07-08 15:38
【摘要】：目的探讨原发性肝癌(HCC)患者氩氦冷冻消融术前外周血中性粒细胞与淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)对患者预后的影响。方法回顾性分析72例HCC患者行经皮穿刺氩氦冷冻消融术的相关临床病理资料。根据术前NLR,分为低NLR组(NLR3.5)和高NLR组(NLR≥3.5),统计分析两组患者术后的总生存期(overall survival,OS),并对其影响预后的危险因素进行单因素和多因素分析。结果所有患者经氩氦冷冻消融治疗后,中位生存期为22.4个月,其中高NLR组的中位生存期为13.2个月,低NLR组的中位生存期为24.2个月,两组中位生存期差异有统计学意义(P=0.003)。单因素分析显示:原发灶大小、肝功能Child-Pugh分级、白蛋白、总胆红素、胆碱酯酶、NLR是影响HCC患者氩氦冷冻消融术后生存期的相关因素(P0.05)。多因素分析显示:原发灶大小和NLR是影响HCC患者氩氦冷冻消融术后生存的独立预后因素(P0.05)。结论术前外周血中NLR可作为HCC患者行氩氦冷冻消融术的预后指标,肝内原发灶越大、NLR越高,患者预后越差。
[Abstract]:Objective to investigate the effect of peripheral blood neutrophils / lymphocytes ratio (neutrophil to lymphocyte ratio,NLR) on prognosis in patients with primary liver cancer (HCC) before argon-he cryoablation. Methods the clinicopathological data of 72 patients with HCC undergoing percutaneous argon-he cryoablation were analyzed retrospectively. According to the preoperative NLR, the patients were divided into low NLR group (NLR3.5) and high NLR group (NLR 鈮，
本文编号：2511691
[Abstract]:Objective to investigate the effect of peripheral blood neutrophils / lymphocytes ratio (neutrophil to lymphocyte ratio,NLR) on prognosis in patients with primary liver cancer (HCC) before argon-he cryoablation. Methods the clinicopathological data of 72 patients with HCC undergoing percutaneous argon-he cryoablation were analyzed retrospectively. According to the preoperative NLR, the patients were divided into low NLR group (NLR3.5) and high NLR group (NLR 鈮，
本文编号：2511691
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