示踪剂技术在腹腔镜直肠癌根治术中应用的价值与意义
发布时间：2021-08-12 00:25
背景和目的直肠癌（rectal cancer）,是最常见的恶性肿瘤之一,死亡率、发病率一直居于恶性肿瘤的前列。其发病原因与多方面因素相关,包括遗传因素、肠道慢性病变、肠道腺瘤病变、高脂低纤维不良饮食习惯等。确诊患者的年龄多位于40岁-50岁年龄组。世界流行病学调查显示,其发病再在西欧、北美、澳大利亚等发达国家发病率最高,但在亚洲、非洲、拉美地区相对较低。直肠癌起病隐匿,早期少有严重的临床表现,就治时多已至中晚期。根治性切除是目前广为接受的治疗直肠癌的主要手段。淋巴转移是主要转移途径,完整清扫转移淋巴结关乎患者预后及术后相关治疗。纳米碳具有淋巴趋向性的特点,可以指导清理淋巴结,弥补既往手术过程中淋巴结清扫的不足。本实验基于以上的研究背景,探讨纳米碳淋巴结示踪剂在腹腔镜直肠癌根治术中应用的价值。资料与方法统计自2017年1月至2019年10月在郑州大学第二附属医院普外科住院行手术治疗的直肠癌患者临床资料行回顾性病例对照研究,共纳入80例患者,均在术前完善MRI、CT、超声等检查明确淋巴结等转移情况。40例患者于术前（1天）肠镜下或肛门镜下肿瘤周围注射纳米碳悬混液后再行腹腔镜直肠癌根治手术。...
【文章来源】：郑州大学河南省 211工程院校
【文章页数】：57 页
【学位级别】：硕士
【部分图文】：
图３．术中黑染淋巴结２??
图２．术中黑染的淋巴结１??
图１术中黑染的肿块区域??
【参考文献】：
期刊论文
[1]结肠癌淋巴结转移程度与预后关系的研究[J]. 刘印,贺利平. 中国普通外科杂志. 2013(04)
[2]Performance value of high risk factors in colorectal cancer screening in China[J]. Wen Meng,Shan-Rong Cai,Lun Zhou,Qi Dong,Shu Zheng,Su-Zhan Zhang,Cancer Institute(Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education,Key Laboratory of Molecular Biology in Medical Sciences,Zhejiang Province,China),The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,Zhejiang Province,China Wen Meng,Department of Cardiothoracic Surgery,Hangzhou First People’s Hospital,Hangzhou 310006,Zhejiang Province,China. World Journal of Gastroenterology. 2009(48)
[3]腹腔镜结肠癌切除术疗效并不亚于开腹手术——基于COST的5年完整随访资料[J]. 陈志辉,Fleshman J,Sargent DJ,Green E. 中华普通外科学文献(电子版). 2009(01)
[4]Assessment of T staging and mesorectal fascia status using high-resolution MRI in rectal cancer with rectal distention[J]. Sheng-Xiang Rao, Meng-Su Zeng, Cai-Zhong Chen, Ren- Chen Li, Department of Radiology, Zhongshan Hospital, Fudan University, and Shanghai Medical Imaging Institute, Shanghai 200032, China Jian-Ming Xu, Xin-Yu Qin, Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China Ying-Yong Hou, Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China. World Journal of Gastroenterology. 2007(30)
[5]前哨淋巴结定位在结直肠癌外科中的应用[J]. 郑阳春. 中国普通外科杂志. 2003(11)
本文编号：3337196
【文章来源】：郑州大学河南省 211工程院校
【文章页数】：57 页
【学位级别】：硕士
【部分图文】：
图３．术中黑染淋巴结２??
图２．术中黑染的淋巴结１??
图１术中黑染的肿块区域??
【参考文献】：
期刊论文
[1]结肠癌淋巴结转移程度与预后关系的研究[J]. 刘印,贺利平. 中国普通外科杂志. 2013(04)
[2]Performance value of high risk factors in colorectal cancer screening in China[J]. Wen Meng,Shan-Rong Cai,Lun Zhou,Qi Dong,Shu Zheng,Su-Zhan Zhang,Cancer Institute(Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education,Key Laboratory of Molecular Biology in Medical Sciences,Zhejiang Province,China),The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,Zhejiang Province,China Wen Meng,Department of Cardiothoracic Surgery,Hangzhou First People’s Hospital,Hangzhou 310006,Zhejiang Province,China. World Journal of Gastroenterology. 2009(48)
[3]腹腔镜结肠癌切除术疗效并不亚于开腹手术——基于COST的5年完整随访资料[J]. 陈志辉,Fleshman J,Sargent DJ,Green E. 中华普通外科学文献(电子版). 2009(01)
[4]Assessment of T staging and mesorectal fascia status using high-resolution MRI in rectal cancer with rectal distention[J]. Sheng-Xiang Rao, Meng-Su Zeng, Cai-Zhong Chen, Ren- Chen Li, Department of Radiology, Zhongshan Hospital, Fudan University, and Shanghai Medical Imaging Institute, Shanghai 200032, China Jian-Ming Xu, Xin-Yu Qin, Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China Ying-Yong Hou, Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China. World Journal of Gastroenterology. 2007(30)
[5]前哨淋巴结定位在结直肠癌外科中的应用[J]. 郑阳春. 中国普通外科杂志. 2003(11)
本文编号：3337196
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