弥漫大B细胞淋巴瘤及NK/T细胞淋巴瘤治疗及预后相关研究
发布时间:2021-10-07 05:39
目的:胃肠道是弥漫大B细胞淋巴瘤(diffuse large B-cell lymphoma,DLBCL)常见的结外受侵部位。目前缺少原发胃DLBCL(PG-DLBCL)和原发肠道DLBCL(PI-DLBCL)临床差异的研究。本研究拟对比分析PG-DLBCL和PI-DLBCL临床特征、治疗模式及预后的差异。方法:回顾性分析2002年12月至2013年1月中国医学科学院肿瘤医院收治的60例PG-DLBCL和41例PI-DLBCL的治疗及生存情况。两组间临床特征比较采用χ2检验,利用Kaplan-Meier法绘制生存曲线。结果:PG-DLBCL和PI-DLBCL患者的中位年龄分别为55岁和48岁,男女患者比例分别为1.14:1和3.1:1。与PG-DLBCL患者相比,大肿块和乳酸脱氢酶水平升高在PI-DLBCL患者中更常见。PG-DLBCL中国际预后指数(International Prognostic Index,IPI)评分为0分、1分和≥2分的患者分别占40.0%、30.0%和30.0%,而PI-DLBCL中IPI评分为0分、1分和≥2分的患者分别占24.4%、29.3%和46.3%...
【文章来源】:北京协和医学院北京市 211工程院校 985工程院校
【文章页数】:94 页
【学位级别】:博士
【部分图文】:
图1-1?PG-DLBCL组和PI-DLBCL组患者的OS?(A)和PFS?(B)生存曲线??
Time?(months)?Time?(months)??图1-1?PG-DLBCL组和PI-DLBCL组患者的OS?(A)和PFS?(B)生存曲线??表^9美罗华联合化疗和单纯化疗组患者的临床特征比较??临床特征?PG-DLBCL,病例数?P1-DLBCL,病例数??R-CHOP?CHOP?p?R-CHOP?CHOP?p??_(n=
图1-3接受手?
【参考文献】:
期刊论文
[1]Addition of rituximab is not associated with survival benefit compared with CHOP alone for patients with stage I diffuse large B-cell lymphoma[J]. Bo Jia,Yuankai Shi,Suyi Kang,Sheng Yang,Shaoxuan Hu,Yexiong Li,Mei Dong,Weihu Wang,Jianliang Yang,Liqiang Zhou,Peng Liu,Shengyu Zhou,Yan Qin,Lin Gui,Changgong Zhang,Hua Lin,Shanshan Chen,Lin Wang,Xiaohui He. Chinese Journal of Cancer Research. 2015(05)
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[3]Efficacy of rituximab in gastric diffuse large B cell lymphoma patients[J]. Davide Leopardo,Giuseppe Di Lorenzo,Amalia De Renzo,Piera Federico,Serena Luponio,Carlo Buonerba,Elide Matano,Gerardina Merola,Martina Imbimbo,Enzo Montesarchio,Antonio Rea,Maria Carmela Merola,Sabino De Placido,Giovannella Palmieri. World Journal of Gastroenterology. 2010(20)
本文编号:3421459
【文章来源】:北京协和医学院北京市 211工程院校 985工程院校
【文章页数】:94 页
【学位级别】:博士
【部分图文】:
图1-1?PG-DLBCL组和PI-DLBCL组患者的OS?(A)和PFS?(B)生存曲线??
Time?(months)?Time?(months)??图1-1?PG-DLBCL组和PI-DLBCL组患者的OS?(A)和PFS?(B)生存曲线??表^9美罗华联合化疗和单纯化疗组患者的临床特征比较??临床特征?PG-DLBCL,病例数?P1-DLBCL,病例数??R-CHOP?CHOP?p?R-CHOP?CHOP?p??_(n=
图1-3接受手?
【参考文献】:
期刊论文
[1]Addition of rituximab is not associated with survival benefit compared with CHOP alone for patients with stage I diffuse large B-cell lymphoma[J]. Bo Jia,Yuankai Shi,Suyi Kang,Sheng Yang,Shaoxuan Hu,Yexiong Li,Mei Dong,Weihu Wang,Jianliang Yang,Liqiang Zhou,Peng Liu,Shengyu Zhou,Yan Qin,Lin Gui,Changgong Zhang,Hua Lin,Shanshan Chen,Lin Wang,Xiaohui He. Chinese Journal of Cancer Research. 2015(05)
[2]培门冬酶治疗儿童白血病研究进展[J]. 刘丽,谢晓恬. 中国当代儿科杂志. 2014(02)
[3]Efficacy of rituximab in gastric diffuse large B cell lymphoma patients[J]. Davide Leopardo,Giuseppe Di Lorenzo,Amalia De Renzo,Piera Federico,Serena Luponio,Carlo Buonerba,Elide Matano,Gerardina Merola,Martina Imbimbo,Enzo Montesarchio,Antonio Rea,Maria Carmela Merola,Sabino De Placido,Giovannella Palmieri. World Journal of Gastroenterology. 2010(20)
本文编号:3421459
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