分化型甲状腺癌术后甲状腺残留的影响因素及其对碘131疗效的影响
发布时间:2021-11-11 23:21
第一章分化型甲状腺癌术后甲状腺残留的影响因素研究目的利用治疗性全身碘131扫描、甲状腺静态显像及颈部超声对分化型甲状腺癌术后甲状腺残留进行分级、描述其演变及分析其影响因素。材料与方法回顾性分析2013年1月至2016年12月在珠江医院核医学科行首次碘131治疗的分化型甲状腺癌患者,联合治疗性全身碘131扫描、甲状腺静态显像及超声对术后甲状腺残留进行分组。采用SPSS 21.0统计软件,用均数±标准差描述连续性变量,用频数(百分比)描述分类变量。分别用方差分析、卡方检验、秩和检验比较不同分组间的差异,再进行有序多分类logistics回归分析。结果共纳入1481例患者。影像学全阴(A组)39(2.6%)例,仅在治疗性全身碘131扫描可见残留甲状腺(B组)422(28.5%)例,治疗性全身碘131扫描及甲状腺静态显像阳性(C组)667(45.0%)例,超声也可探查残留甲状腺(D+E组)353(23.8%)例。从2014年前到2016年,D+E组比例从30.0%降到16.2%,C组的比例从39.4%增长到61.0%。在单因素分析中,侵犯神经、医院等级、手术次数及淋巴结清扫范围与术后甲状腺残留...
【文章来源】:南方医科大学广东省
【文章页数】:61 页
【学位级别】:硕士
【部分图文】:
图1-2?(B组)??33岁,女,双侧甲状腺近全切术后,治疗性碘131扫描(a)中甲状腺床处可见2处类??
?第一章分化型甲状腺癌术后甲状腺残留的影响因素???n.?HR??图1_1?(A组)??30岁,女,甲状腺根治术后,三种影像学检查中都未发现甲状腺残留(a:治疗性碘131??扫描,b:甲状腺静态显像,c:超声)。??Figurel-1?(A?Group)??A?30-year-old?female?patient?after?radical?thyroidectomy.lt?showed?no?thyroid?remnant?in?the??three?imaging?methods?(a:?post-Rx?WBS,b:Thyroid?scintigraphy,c:Ultrasonography).??图1-2?(B组)??33岁,女,双侧甲状腺近全切术后,治疗性碘131扫描(a)中甲状腺床处可见2处类??圆形放射性碘摄取,甲状腺静态显像(b)及超声检查(c)未发现甲状腺残留。??Figure?1-2?(B?Group)??A?33-year-old?female?patient?after?near-total?thyroidectomy.Post-Rx?WBS(a)?showed?two??round-shape?radioactive?iodine?uptake?lesions?in?the?thyroid?bed,but?thyroid?scintigraphy(b)?and??ultrasonography(c)?were?negative.??-12??
?颂士学位论文???’丨??w??图1-3?(C组)??43岁,女,双侧甲状腺全切术后,治疗性碘131扫描(a)及甲状腺静态显像(b)都??可见明显残留甲状腺,超声检查(c)未发现甲状腺残留??Figure?1-3?(C?Group)??A?43-year-old?female?patient?with?total?thyroidectomy.Post-Rx?WBS(a)?showed?severe??radioactive?iodine?uptake?lesions?in?the?thyroid?bed,and?thyroid?scintigraphy(b)?also?showed??obvious?uptake?in?the?left?of?thyroid.?Ultrasonography(c)?failed?to?visualize?the?presence?of??thyroid?remnant.??瞧應:??图1?-4?(D组)??34岁,男,甲状腺根治术后,三种影像学检查都可见明显残留甲状腺(a:治疗性碘131??扫描,b:甲状腺静态显像,c:超声)??Figure?1-4?(D?Group)??A?34-year-old?male?patient?after?radical?thyroidectomy.The?three?imaging?methods?(a:??post ̄Rx?WBS,?b:Thyroid?scintigraphy,?c:Ultrasonography)?detected?severe?remnant?in?the?left?of??thyroid?bed.??-13??
【参考文献】:
期刊论文
[1]分化型甲状腺癌术后131Ⅰ治疗生存率分析[J]. 余永利,罗全勇,陈立波,罗琼,丁颖,陆汉魁,朱瑞森,马寄晓. 中华核医学杂志. 2006(05)
硕士论文
[1]大剂量131碘致分化型甲状腺癌患者唾液腺损伤的临床研究[D]. 吴菊清.南方医科大学 2014
本文编号:3489738
【文章来源】:南方医科大学广东省
【文章页数】:61 页
【学位级别】:硕士
【部分图文】:
图1-2?(B组)??33岁,女,双侧甲状腺近全切术后,治疗性碘131扫描(a)中甲状腺床处可见2处类??
?第一章分化型甲状腺癌术后甲状腺残留的影响因素???n.?HR??图1_1?(A组)??30岁,女,甲状腺根治术后,三种影像学检查中都未发现甲状腺残留(a:治疗性碘131??扫描,b:甲状腺静态显像,c:超声)。??Figurel-1?(A?Group)??A?30-year-old?female?patient?after?radical?thyroidectomy.lt?showed?no?thyroid?remnant?in?the??three?imaging?methods?(a:?post-Rx?WBS,b:Thyroid?scintigraphy,c:Ultrasonography).??图1-2?(B组)??33岁,女,双侧甲状腺近全切术后,治疗性碘131扫描(a)中甲状腺床处可见2处类??圆形放射性碘摄取,甲状腺静态显像(b)及超声检查(c)未发现甲状腺残留。??Figure?1-2?(B?Group)??A?33-year-old?female?patient?after?near-total?thyroidectomy.Post-Rx?WBS(a)?showed?two??round-shape?radioactive?iodine?uptake?lesions?in?the?thyroid?bed,but?thyroid?scintigraphy(b)?and??ultrasonography(c)?were?negative.??-12??
?颂士学位论文???’丨??w??图1-3?(C组)??43岁,女,双侧甲状腺全切术后,治疗性碘131扫描(a)及甲状腺静态显像(b)都??可见明显残留甲状腺,超声检查(c)未发现甲状腺残留??Figure?1-3?(C?Group)??A?43-year-old?female?patient?with?total?thyroidectomy.Post-Rx?WBS(a)?showed?severe??radioactive?iodine?uptake?lesions?in?the?thyroid?bed,and?thyroid?scintigraphy(b)?also?showed??obvious?uptake?in?the?left?of?thyroid.?Ultrasonography(c)?failed?to?visualize?the?presence?of??thyroid?remnant.??瞧應:??图1?-4?(D组)??34岁,男,甲状腺根治术后,三种影像学检查都可见明显残留甲状腺(a:治疗性碘131??扫描,b:甲状腺静态显像,c:超声)??Figure?1-4?(D?Group)??A?34-year-old?male?patient?after?radical?thyroidectomy.The?three?imaging?methods?(a:??post ̄Rx?WBS,?b:Thyroid?scintigraphy,?c:Ultrasonography)?detected?severe?remnant?in?the?left?of??thyroid?bed.??-13??
【参考文献】:
期刊论文
[1]分化型甲状腺癌术后131Ⅰ治疗生存率分析[J]. 余永利,罗全勇,陈立波,罗琼,丁颖,陆汉魁,朱瑞森,马寄晓. 中华核医学杂志. 2006(05)
硕士论文
[1]大剂量131碘致分化型甲状腺癌患者唾液腺损伤的临床研究[D]. 吴菊清.南方医科大学 2014
本文编号:3489738
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