参天止动汤治疗多发性抽动症脾虚肝亢型临床观察

发布时间：2017-12-28 05:08

本文关键词：参天止动汤治疗多发性抽动症脾虚肝亢型临床观察　出处：《黑龙江中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探察参天止动汤对小儿多发性抽动症脾虚肝亢型的治疗效果及副作用。方法:本次课题的样本选自符合纳入标准的多发性抽动症的患儿60例,应用随机分组法,将其分为治疗组和对照组各30例。其中治疗组给以患儿口服参天止动汤,对照组予盐酸硫必利片,并对两组患儿家长进行教育宣传和指导病情。治疗共8周,后进行两组综合疗效评定对比,包括总疗效、耶鲁抽动量表积分程度的改善、运动和发声抽动的改善以及中医症候的改善情况。随访2个月,观察副作用。结果:经8周医治后,在抽动方面治疗组的总有效率为96.67%,对照组的总有效率为86.67%,两组总疗效有明显差异(P0.05),表明治疗组的总有效率明显高于对照组;而中医症候总有效率治疗组为100.00%,对照组为63.33%,p0.05,治疗组显著优于对照组。两组组内在用药前后进行对比,在YGTSS积分和中医症候积分两个方面的差异均具有统计学意义(P0.05),即治疗有效;两组样本治疗后比较,治疗组和对照组同样在以上两方面差异具有统计学意义(P0.05),表明治疗组疗效明显优于对照组。治疗组不存在不良事件,对照组存在2例。结论:1.参天止动汤治疗儿童多发性抽动症脾虚肝亢型优于西药盐酸硫必利片,在减轻YGTSS积分值、中医症候方面均有显著差异。2.参天止动汤无毒副作用,安全可靠,进一步证实中医药治疗小儿多发性抽动症的特色和优势。
[Abstract]:Objective: to detect the towering stopper and the side effect of spleen deficiency and liver hyperactivity in children with tic Decoction multiple treatment effect. Methods: the samples from 60 children with Tourette's disease who were in accordance with the inclusion criteria were randomly divided into two groups: the treatment group and the control group, 30 cases in each group. In the treatment group, the children were given oral anti motion soup, the control group was given Tiapride Hydrochloride Tablets, and the parents of the two groups were educated and instructing the condition. After 8 weeks of treatment, the two groups were compared for the comprehensive efficacy evaluation, including the total efficacy, the improvement of Yale tic scale, the improvement of exercise and vocal tics, and the improvement of TCM symptoms. After 2 months of follow-up, side effects were observed. Results: after 8 weeks after treatment in the treatment group, with the total effective rate was 96.67%, the total efficiency of the control group was 86.67%, there was significant difference between the total effect of the two groups (P0.05), shows that the total efficiency of the treatment group was significantly higher than the control group; and the TCM syndrome total effective rate of treatment group was 100%, control group 63.33%, P0.05, the treatment group was significantly better than the control group. The two groups before and after medication were compared within groups, differences in the two aspects of integral YGTSS and TCM symptoms were statistically significant (P0.05), the treatment is effective; two groups were compared after treatment, the treatment group and the control group in the above two aspects of the differences were statistically significant (P0.05), showed that the curative effect of treatment group was better than the control group. There were no adverse events in the treatment group, and there were 2 cases in the control group. Conclusion: 1.. The application of "Tian Zhi Zhi Tang" in treating children with Tourette syndrome, spleen deficiency and liver hyperactivity is better than western medicine Tiapride Hydrochloride Tablets, and has significant difference in reducing YGTSS integral value and TCM symptoms. 2. Shen Zhi Zhi Tang has no toxic and side effects, and it is safe and reliable. It further confirms the characteristics and advantages of Chinese medicine in the treatment of children with multiple Tourette syndrome.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.7

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