中药补肾化瘀法对子宫内膜异位囊肿术后（肾虚血瘀证）的临床研究

发布时间：2017-12-30 17:37

本文关键词：中药补肾化瘀法对子宫内膜异位囊肿术后（肾虚血瘀证）的临床研究　出处：《长春中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:探讨中药补肾化瘀法对子宫内膜异位囊肿术后(肾虚血瘀证)的作用机制,以寻求治疗该疾病的安全有效的方案。方法:将72例OEC术后患者随机分为两组,对照组36例,在术后1周给予米非司酮口服,10mg/次,1次/日。治疗组在其基础上,予以补肾益气、化瘀止痛中药免煎颗粒口服,1剂/日,早晚温服,两组均服药3个月,1个疗程,共观察1个疗程;并系统观察两组患者痛经改善情况、中医证候积分、体征的变化,彩超前后对比,用药不良反应及复发率等,进行统计学分析。结果:临床研究显示,两种治疗方法均能有效改善临床症状、痛经程度、降低血清CA1 2 5水平及复发率,两组比较,差异无显著性意义(P0.05);而在改善中医证候、体征方面,用药期间的不良反应方面比较,差异有显著性意义(P0.05),中药可有效改善患者的中医证候、体征,且没有不良反应。结论:中药补肾化瘀法联合米非司酮片对于OEC术后肾虚血瘀证的患者疗效有效,能够改善临床症状、体征、痛经程度、降低血清CA1 2 5水平及术后的复发率,且不良反应小,值得在临床使用。
[Abstract]:Objective: to explore the mechanism of traditional Chinese medicine Bushen Huayu method on endometriosis after operation (kidney deficiency and blood stasis syndrome). Methods: 72 patients with OEC were randomly divided into two groups: the control group (36 cases) was given mifepristone orally 10 mg / time at one week after operation. Once a day. On the basis of the treatment group, the treatment group was treated with tonifying kidney and tonifying qi, removing blood stasis and relieving pain by taking one dose per day, taking warm medicine in the morning and evening, both groups taking medicine for 3 months, a course of treatment, and observing a course of treatment altogether; And the two groups of patients with dysmenorrhea improvement, TCM syndromes score, changes of signs, color ultrasound before and after contrast, drug adverse reactions and recurrence rate, statistical analysis. Results: clinical study showed. The two treatment methods can effectively improve clinical symptoms, dysmenorrhea, reduce serum CA1 25 level and recurrence rate, there is no significant difference between the two groups (P 0.05). In improving TCM syndromes, signs, adverse reactions during medication, the difference is significant (P0.05A), Chinese medicine can effectively improve the TCM syndromes, signs. Conclusion: traditional Chinese medicine Bushen Huayu method combined with mifepristone tablet is effective for patients with kidney deficiency and blood stasis syndrome after OEC, and can improve clinical symptoms, signs and dysmenorrhea. The level of serum CA1 25 and the recurrence rate after operation were decreased, and the adverse reaction was small, which was worthy of clinical use.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.9

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