基于数据挖掘的含翼首草藏药组方用药规律研究

发布时间：2017-12-31 04:02

本文关键词：基于数据挖掘的含翼首草藏药组方用药规律研究　出处：《中国中药杂志》2017年16期 　论文类型：期刊论文

【摘要】：该研究在收集含翼首草处方的基础上,利用"中医传承辅助平台(V2.0.1)"软件构建数据库,采用关联规则、apriori算法等数据挖掘方法,探讨分析《中国医学百科全书-藏医学》、《藏医成方制剂现代研究与临床应用》、《常用藏成药诠释》等含翼首草组方中翼首草用药规律。分析含翼首草处方中单味药物频次、药物组合频次、关联规则与核心药物组合等。通过处方收集最终纳入方剂215首,共涉及376味药材。通过"频次统计",分析出含翼首草的处方主要治疗感冒发热,瘟毒及各种温热病与关节炎疾病等。高频药物(频次≥15)包括矮紫堇、藏黄连、麻花秦艽等。高频药物组合包括"翼首草、矮紫堇"、"翼首草、藏黄连"、"翼首草、麻花秦艽"等。含翼首草处方主治疾病主要为外感湿热秽毒类病证、发热类、关节炎等疾病,如瘟毒、肺炎以及流行性感冒、类风湿关节炎等,所用药物多具清热解毒、消炎、祛风除湿等功效,亦常与清热类药物配伍运用,用药较为集中,组方法度清晰。
[Abstract]:Based on the collection of yishoucao containing prescription, the use of "TCM inheritance auxiliary system (V2.0.1) software to build the database, using the Apriori algorithm of association rules, data mining methods such as analysis of Chinese Medical Encyclopedia - < > < Tibetan medicine, Tibetan medicine prescription preparation for modern research and clinical application of < >, commonly used in Tibetan medicine the interpretation of such drug laws of pterocephali Herba pterocephali Herba > containing formula. Analysis of single drug prescription in high frequency, frequency of drug combination, association rules and the core drug combination. Through collecting prescription ultimately included 215 prescriptions, involving a total of 376 medicinal materials. Through the statistical analysis, including pterocephali Herba prescribed mainly for colds fever, plague virus and various febrile disease and arthritis disease. High frequency drugs (frequency = 15) including dwarf Corydalis, Tibetan Coptis, etc.. The high frequency of Gentiana straminea drug combinations including" wing of the first grass, dwarf, licorice, corydalis "Tibet" "," pterocephali Herba, Coptis Gentiana "etc. containing yishoucao prescription indications of disease is mainly caused by the dampness heat syndrome and toxic, fever, arthritis and other diseases, such as plague virus, pneumonia and influenza, rheumatoid arthritis, drugs used with detoxification, anti-inflammatory and other effects, Qufengchushi, they often heat drugs and compatibility of the use, medication is more concentrated, group method is clear.

【作者单位】：成都中医药大学;
【基金】：国家自然科学基金项目(81274193)
【分类号】：R29
【正文快照】： 翼首草是藏医常用药材,来源于川续断科翼首花属植物匙叶翼首花Pterocephalus hookeri(C.B.Clarke)H9eck.或裂叶翼首花P.bretschneider(i Batal.)Pritz.的根或全草[1]。翼首草味苦,性寒,有小毒,有解毒、清热止痢、祛风除痹之功效。藏药名为“榜孜毒乌”,又名“榜姿多沃”。藏医

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