西黄胶囊治疗粉刺性乳痈的临床疗效观察

发布时间：2017-12-31 06:18

本文关键词：西黄胶囊治疗粉刺性乳痈的临床疗效观察　出处：《河南中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:本文旨在研究西黄胶囊对于粉刺性乳痈患者的治疗作用,探寻西黄胶囊治疗粉刺性乳痈的疗效和药物作用的途径,为西黄胶囊治疗粉刺性乳痈提供临床和科研的基础。方法:收集2015年3月至2015年10月河南省中医院乳腺科门诊初收治的粉刺性乳痈患60例。所纳入的患者绝大部分有乳腺肿块、乳腺红肿热痛以及脓肿形成,部分已形成瘘管或窦道。西黄胶囊出自西黄丸,其功效为清热解毒、化痰散结、活血化瘀、消肿止痛,组成成分为牛黄、麝香、乳香和没药。本研究通过观察粉刺性乳痈患者的临床表现和血液的检查结果,给予口服西黄胶囊治疗,记录治疗过程中的临床表现,血细胞分析、CRP及性激素六项等指标的变化;并对入组的患者进行定期随访,运用SPSS18.0软件进行统计分析并评价。结果:(1)应用西黄胶囊为主治疗粉刺性乳痈患者2周、4周后总有效率分别为43.33%、93.33%,乳房肿块治疗前后明显缩小,皮肤红肿症状亦缓解明显,经统计学分析有显著差异,P0.01。(2)治疗后WBC、NE%、CRP计数下降,均有统计学意义P0.05。(3)治疗后性激素六项指标与治疗前相比较有不同程度的下降,但雌激素、孕激素、睾酮、促黄体生成素、促卵泡生成素及泌乳素的指标同治疗前相比较,均无统计学意义,即P0.05。结论:(1)西黄胶囊治疗粉刺性乳痈的疗效肯定,值得临床推广和应用。(2)西黄胶囊治疗粉刺性乳痈可能与其抗炎功效有关。(3)调节内分泌功能可能是西黄胶囊治疗粉刺性乳痈的一个重要机理。
[Abstract]:Objective: To study the effect of Xihuang Capsules for the treatment of plasma cell mastitis patients, explore the curative effect and drug effect way Xihuang Capsules in the treatment of acne of acute mastitis, provide the basis for clinical and scientific research for Xihuang Capsules in the treatment of plasma cell mastitis. Methods: from March 2015 to October 2015 in Henan Traditional Chinese Medicine Hospital outpatient breast early treated 60 patients with plasma cell mastitis. Patients with most breast lumps, breast swelling and heat pain and abscess formation, part has formed a fistula or sinus. From Xihuang Pill Xihuang Capsules, the effect of heat clearing and detoxifying, phlegm, blood stasis, detumescence and acesodyne, composition of bezoar, musk, frankincense and myrrh. This research through clinical observation performance and blood plasma cell mastitis patients to check the results, given oral Xihuang Capsules treatment, record the clinical manifestations in the course of treatment, blood cell analysis, CRP The changes of sex hormones and six other indicators; and in the group of patients were regularly followed up for statistical analysis and evaluation by SPSS18.0 software. Results: (1) the application of Xihuang Capsules treatment of plasma cell mastitis in 2 weeks, 4 weeks after the total efficiency were 43.33%, 93.33%, breast lumps before and after treatment was significantly reduced also, the symptoms of skin irritation was relieved, the statistical analysis had significant differences, P0.01. (2) after treatment, WBC, NE%, CRP counts decreased, had statistical significance (3 P0.05.) after the treatment of sex hormone six indicators compared with before treatment were decreased, but different degree of estrogen, progesterone, testosterone, luteinizing in the follicle stimulating hormone index and lactation compared with before treatment, were not statistically significant, P0.05. (1) conclusion: the curative effect of Xihuang Capsules in the treatment of plasma cell mastitis, is worthy of promotion and application. (2) xihunag capsule in the treatment of acne lotion Carbuncle may be related to anti-inflammatory effect. (3) the regulation of endocrine function may be an important mechanism of Xihuang capsule in the treatment of plasma cell mastitis.

【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R269

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