伤科黄水治疗急性痛风性关节炎的临床研究

发布时间：2017-12-31 21:22

  本文关键词：伤科黄水治疗急性痛风性关节炎的临床研究　出处：《广州中医药大学》2017年硕士论文　论文类型：学位论文

  更多相关文章： 痛风性关节炎 急性期 伤科黄水 临床疗效 安全性

【摘要】：目的:通过观察经伤科黄水外敷治疗后急性痛风性关节炎患者的血沉、C-反应蛋白、血尿酸、VAS评分、临床症状体征等指标的变化,评估伤科黄水的临床疗效及安全性。方法:计算机软件生成随机数字,按入组顺序随机将确诊为急性痛风性关节炎患者90例分为治疗组和对照组,每组各45例。对照组予秋水仙碱片(0.5mgP.Otid)治疗;治疗组在此基础上,加用伤科黄水外敷病变关节处。每组疗程均为1周。观察两组患者治疗前后的ESR、CRP、UA、VAS评分、临床症状积分、临床疗效、不良反应等指标的变化,客观综合评价外敷伤科黄水治疗急性痛风性关节炎的临床疗效、安全性。结果:①两组间的基线指标均无显著性差异(P0.05)。②两组患者的ESR、CRP、VAS评分在治疗前无显著差异(P0.05)。治疗后,两组患者的ESR、CRP、VAS评分较治疗前均有显著降低(P0.05),且治疗组的降低程度较对照组更为明显(P0.05)。③两组患者的血尿酸水平在治疗前无显著差异(P0.05)。治疗后,两组患者血尿酸水平较治疗前降低(P0.05),但治疗组的血尿酸下降幅度较对照组无显著性差异(P0.05)。④两组治疗前临床症状积分比较,差异无统计学意义(P0.05);两组治疗后的临床症状积分较治疗前均降低(P0.05);且治疗组的治疗后临床症状积分明显低于对照组,差异有统计学意义(P0.05)。⑤治疗后,治疗组显效15例(33.33%),有效27例(60%),无效3例(6.67%),总有效率93.33%。对照组显效11例(13.33%),有效25例(66.67%),无效9例(20%),总有效率为80%。在临床疗效上治疗组显著优于对照组(P0.05)。⑥治疗后,两组患者出现的不良反应无统计学意义(P0.05)。结论:①伤科伤科黄水能够降低急性痛风性关节炎患者的炎症指标、VAS评分、临床症状积分。②伤科伤科黄水联合西药治疗急性痛风性关节炎患者较单纯西药具有明显临床疗效。③伤科伤科黄水治疗急性痛风性关节炎安全有效,值得推广,可成为一种有效的中医治疗方法。
[Abstract]:Objective: To observe the water treatment after ESR Department of Traumatology patients with acute gouty arthritis, C- reactive protein, uric acid, VAS score, changes of clinical symptoms and signs such as indicators of the evaluation of clinical efficacy and safety of Department of Traumatology water. Methods: computer software to generate random numbers, according to the group order were diagnosed as 90 cases of acute gouty arthritis patients were divided into treatment group and control group, 45 cases in each group. The control group was treated with Colchicine Tablets (0.5mgP.Otid) treatment; treatment group on the basis of this, combined with the Department of Traumatology and topical lesion joints. Each group was treated for 1 weeks. Observe two groups of patients before and after treatment of ESR, CRP, UA. VAS score, clinical symptom score, clinical efficacy, adverse reactions and other indicators of change, clinical efficacy, objective evaluation of external water department of Traumatology for treatment of acute gouty arthritis safety. Results: the baseline characteristics between the two groups were not significant 鎬у樊寮，

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