腻苔形成的生物学机制

发布时间：2018-01-01 03:01

本文关键词：腻苔形成的生物学机制　出处：《中华中医药杂志》2017年03期 　论文类型：期刊论文

【摘要】：腻苔是一种临床常见的病理性舌苔,主湿浊、痰饮、食积等,在中医临床诊断与治疗中有重要的临床意义与辨证价值,研究腻苔形成的现代生物学机制有重要的理论和实践意义。文章从舌表面脱落细胞学、微生态学、相关蛋白与基因表达及物质代谢等方面对腻苔形成的生物学机制进行了综述,并对腻苔与肠道微生态的关系,腻苔与现代医学疾病的关系进行了阐述,以期从现代生物医学角度对腻苔形成的物质基础、发生机制、变化规律及与相关疾病的关系作相关阐明,为疾病的中医诊断与治疗提供借鉴和帮助。
[Abstract]:Greasy fur is a kind of common pathological tongue coating, which is characterized by dampness, phlegm, food accumulation and so on. It has important clinical significance and syndrome differentiation value in the clinical diagnosis and treatment of traditional Chinese medicine. It is of great theoretical and practical significance to study the modern biological mechanism of greasy fur formation. The biological mechanism of greasy fur formation was reviewed in the aspects of protein and gene expression and substance metabolism. The relationship between greasy fur and intestinal microecology and between greasy fur and modern medical diseases was also discussed. From the perspective of modern biomedicine, the material basis, the mechanism of greasy fur formation, the law of change and the relationship between greasy fur and related diseases can be elucidated in order to provide reference and help for the diagnosis and treatment of diseases in traditional Chinese medicine.
【作者单位】：厦门大学医学院中医系;广州中医药大学临床药理研究所;
【基金】：国家重点研发计划重点专项(No.2016YFC1305903) 教育部“新世纪优秀人才支持计划”(No.NCET-13-0505) 国家自然科学基金项目(No.81373999,No.30572362,No.30100240)~~
【分类号】：R241.25
【正文快照】： 舌诊是中医诊断体系中的一项重要诊断方法,清代章楠《医门棒喝·伤寒论本旨》记载:“观舌体,可验其阴阳虚实,审舌垢,即知其邪之寒热浅深也”。这里的舌垢即是舌苔。中医理论认为舌苔是胃气蒸化谷气上承于舌面而形成,与脾胃运化功能密切相关。腻苔是一种常见的病理性舌苔,有重

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