骨宝胶囊治疗老年男性原发性骨质疏松症的临床观察

发布时间：2018-01-01 04:24

本文关键词：骨宝胶囊治疗老年男性原发性骨质疏松症的临床观察　出处：《山东中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：研究目的:通过观察骨宝胶囊用于治疗老年男性肝肾不足型原发性骨质疏松症临床疗效,运用滋肝补肾法并配合钙补充剂及抗骨质疏松药物治疗老年男性原发性骨质疏松症,探索讨论中药与西药制剂结合治疗该病的优势及临床可行性。研究方法:收集患有老年男性原发性骨质疏松症的老年男性患者60例。随机分为试验组和对照组,两组均给予钙尔奇D和阿法迪三基础治疗,根据病情轻重给予抗骨质疏松药物如福善美、密盖息、密固达治疗,在此基础上,试验组患者加用骨宝胶囊口服治疗。临床观察6个月,记录两组患者临床表现及实验室检查结果。研究成果:经过临床疗效比较,中医症状评分对比,试验组有效率明显高于对照组,且具有统计学意义。治疗前后,两组患者临床症状、骨转换指标、睾酮均有明显差异性,试验组优于对照组。结论:在基础治疗及抗骨质疏松治疗外,加用骨宝胶囊治疗效果明显,骨宝胶囊治疗老年男性肝肾不足型原发性骨质疏松症的治疗效果显著,且无明显不良反应。该法毒副作用小,安全,方便患者接受,与钙补充剂共用作用良好,值得临床应用、推广。
[Abstract]:Objective: through the observation of Gubao capsule for the treatment of elderly primary liver and kidney deficiency type clinical curative effect of osteoporosis by nourishing the liver and kidney method combined with calcium supplements and anti osteoporosis drugs for the treatment of elderly male patients with primary osteoporosis, traditional Chinese medicine and Western medicine preparation combined with exploratory discussion and clinical feasibility of the treatment of the disease. Methods: the study was collected with elderly male elderly male patients with primary osteoporosis. 60 cases were randomly divided into experimental group and control group, two groups were given Caltrate D and Afadi three basic treatment, according to the severity of given anti osteoporosis drugs such as Fosamax, Miacalcic, Aclasta in this treatment. On the basis, with Gubao capsules for treatment of patients in the experimental group. The clinical observation of 6 months, recording two groups of patients with clinical manifestation and laboratory examination results. Results: after the comparison of the clinical efficacy, TCM symptoms Score between the experimental group was significantly higher than the control group, and have statistical significance. Before and after treatment, two groups of patients with clinical symptoms, bone turnover markers, significant differences in testosterone were the experimental group than the control group. Conclusion: on the basis of the treatment and treatment of osteoporosis with Gubao capsule, the treatment effect is obvious, bone capsule treatment significantly in elderly male liver and kidney deficiency type osteoporosis treatment effect, and no obvious adverse reactions. The side effects of small, safe, convenient for patients, good and common function of calcium supplements, it is worthy of clinical application and promotion.

【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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