推拿治疗小儿厌食症随机对照试验的系统评价和Meta分析

发布时间：2018-01-01 06:30

本文关键词：推拿治疗小儿厌食症随机对照试验的系统评价和Meta分析　出处：《中华中医药学刊》2017年05期 　论文类型：期刊论文

【摘要】：目的:系统评价单纯推拿疗法治疗小儿厌食症的有效性。方法:以"小儿厌食症"、"推拿"、"捏脊"、"infantile anorexia"等为主题词,检索Pub Med数据库、Cochrane图书馆、中国知网数据库、维普中文科技期刊数据库、中国生物医学文献数据库及万方数据库。所有数据库检索时间从建库开始截止至2015年10月10日。由两名评价者独立提取资料,并根据Jadad改良法制定量表进行文献质量评价。采用Cochrane协作网提供的Rev Man5.3软件进行Meta分析。结果:(1)临床总有效率分析:推拿对比中药(RR:1.14;95%CI:1.05,1.24;P=0.002),差异有统计学意义,推拿对比西药(RR:1.42;95%CI:1.31,1.55;P0.000 01),差异有统计学意义;(2)临床症状总积分改善分析:推拿对比中药(WMD:-3.93;95%CI:-7.91,0.06;P=0.05),差异无统计学意义,推拿对比西药(WMD:-2.00;95%CI:-2.43,-1.56;P0.000 01),差异有统计学意义。结论:推拿治疗小儿厌食症疗效优于中药及西药,且相对于西药可以明显缓解临床综合症状。但是纳入评价的文献质量偏低,仍需要多中心、大样本的更规范的随机对照试验加以验证。
[Abstract]:Objective: to evaluate the effectiveness of simple massage therapy in the treatment of infantile anorexia. Methods: "Pediatric anorexia", "massage", "chiropractic". "infantile anorexia" was used as the subject word to search the Pub Med database. Database of Chinese Science and Technology Journals. Chinese Biomedical Literature Database and Wanfang Database. The retrieval time of all databases is from the beginning of the database construction to October 10th 2015. The data are extracted independently by two evaluators. According to the improved method of Jadad, the quality of literature was evaluated. The Meta analysis was carried out with Rev Man5.3 software provided by Cochrane Cooperative Network. The results were as follows: 1). Total effective rate analysis: compared with Chinese herbal medicine RR: 1.14; 95 CI: 1.05U 1.24; The difference was statistically significant (P < 0.002), compared with that of western medicine (RR: 1.42). 95 CI: 1.31 and 1.55; P0.00001, the difference was statistically significant. 2) Analysis on the improvement of total clinical symptom score: WMD: 3.93; 95 CI: -7.91 0. 06; The difference was not statistically significant (P < 0.05), and compared with that of western medicine (WMD: 2.00); 95 CI: -2.43% -1.56; Conclusion: the therapeutic effect of massage on anorexia in children is better than that of traditional Chinese medicine and western medicine. But the quality of the literature included in the evaluation is low, and it still needs to be verified by a more standard randomized controlled trial with many centers and large samples.
【作者单位】：北京中医药大学;
【基金】：国家自然科学基金项目(81373759) 高等学校博士学科点专项基金项目(20130013110013)
【分类号】：R244.1
【正文快照】： 小儿厌食症[1]是以小儿食欲减退、食量减少为主要症状的食欲障碍性疾病。本病多发于1~6岁小儿,城市儿童发病率较高[2]。研究表明[3]小儿厌食症的发病与多种因素相关,如性格胆怯、强迫进食、过多零食、血锌值偏低等。厌食症状如果长期无法改善,会导致患儿出现免疫力下降及营养

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