益肺灸对慢性阻塞性肺疾病生存质量的影响

发布时间：2018-01-01 13:09

本文关键词：益肺灸对慢性阻塞性肺疾病生存质量的影响　出处：《河南中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:观察慢性阻塞性肺疾病(COPD)稳定期患者的CAT问卷、SF-36量表、患者临床报告结局、疗效满意度和皮肤致敏评价等结局指标,评价益肺灸治疗对COPD患者生存质量的影响。方法:采取随机对照的分组方法,将COPD稳定期患者分为试验组60例和对照组60例,试验组在维持原有治疗的基础上配合益肺灸治疗,对照组维持原有治疗,治疗3个月。以患者CAT问卷、SF-36量表、患者临床报告结局、疗效满意度、皮肤致敏评价为结局指标。采用SPSS20.0进行统计分析。结果:共纳入患者120例,脱落18例,有效患者共102例,其中试验组50例,对照组52例。两组基线无统计学差异,具有可比性。临床观察如下:1.CAT问卷治疗前,两组CAT评分无统计学意义(P0.05)。治疗后,两组间CAT评分比较有统计学差异(P0.05)。治疗后,试验组CAT评分下降较治疗前显著(P0.01),对照组CAT评分较治疗前下降(P0.05)。2.SF-36量表治疗前,两组生理机能、一般健康、生理职能、精力、情感职能、社会功能、身体疼痛和精神健康得分均无统计学意义(P0.05)。治疗后两组间除精神健康和情感职能得分无统计学意义(P0.05)外,其余方面得分比较均有统计学差异(P0.05)。治疗后,试验组除精神健康和情感职能得分较治疗前比较差异无统计学意义(P0.05)外,其余方面得分较治疗前升高(P0.05),对照组除身体疼痛、精神健康和情感职能得分较治疗前比较差异无统计学意义(P0.05)外,其余方面得分较治疗前升高(P0.05)。3.COPD病人报告的临床结局(COPD-PRO)治疗前,两组患者临床症状评分、疗效满意度评分、健康满意度评分和COPD-PRO总评分无统计学意义(P0.05)。治疗后两组间上述各领域评分比较有统计学意义(P0.05)。治疗后,试验组上述各领域评分较治疗前下降显著(P0.01),对照组除健康满意度评分较治疗前比较差异无统计学意义(P0.05)外,其余各领域评分较治疗前下降(P0.05)。4.患者疗效满意度(ESQ-COPD)治疗前,两组临床症状评分、治疗效果评分、总体疗效评分、工作生活能力评分和ESQ-COPD总评分无统计学差异(P0.05)。治疗后两组间上述领域评分比较均有统计学差异(P0.05)。治疗后试验组上述各领域评分较治疗前比较升高显著(P0.01),对照组除临床症状评分评分较治疗前比较差异均无统计学意义(P0.05),其余各领域评分较治疗前比较升高(P0.05)。在治疗方便评分方面,治疗前后两组间比较和两组治疗前后比较均无统计学意义(P0.05)。5.皮肤致敏评价治疗期间两组发生皮肤致敏反应无统计学意义(P0.05)。试验组在治疗1个月期间有2例患者出现皮肤明显红斑,评分等于2分判定为致敏阳性;治疗3个月期间有4例患者出现皮肤致敏阳性,1例表现为轻微红斑伴轻微水肿,另3例表现为明显红斑。治疗后试验组共6例患者出现皮肤致敏阳性,致敏率为4%,致敏等级属Ⅰ级,致敏强度弱。对照组未进行益肺灸治疗。结论:1益肺灸治疗能改善COPD稳定期患者临床症状,改善日常工作生活和交往能力,使患者生存质量得到一定改善。2益肺灸治疗能提高患者的治疗效果,对患者的疗效满意度具有一定的改善。3益肺灸治疗皮肤致敏强度弱,发生皮肤致敏率低。
[Abstract]:Objective: To observe the effect of chronic obstructive pulmonary disease (COPD) patients with stable CAT questionnaire, SF-36 scale, patients reported outcomes, curative effect satisfaction and skin sensitization evaluation outcome indicators, impact on quality of life in patients with the treatment of COPD evaluation of Yifei moxibustion. Methods: according to the method of random grouping, the patients with COPD the stable period is divided into 60 cases of test group and 60 cases in the control group, experimental group with Yifei moxibustion therapy based on maintaining the original treatment, the control group was given conventional treatment, treatment for 3 months. The patients with CAT questionnaire, SF-36 scale, the satisfaction of patients with clinical outcome, report, skin sensitization evaluation outcome. SPSS20.0 was used for statistical analysis. Results: 120 patients were included, 18 cases of loss, effective with a total of 102 cases, 50 cases in test group, 52 cases in the control group. No significant difference between the two groups at baseline, comparable. Clinical observation as follows: 1.CAT questionnaire before treatment, The CAT scores of the two groups had no statistical significance (P0.05). After the treatment, CAT scores between the two groups was statistically significant (P0.05). After treatment, the test group CAT score decreased significantly compared with those before treatment (P0.01), the control group CAT score decreased (P0.05).2.SF-36 scale before treatment, two groups of physiological function, general health, physiological function, energy, emotional function, social function, physical pain and mental health scores were not statistically significant (P0.05). After treatment between the two groups in the scores of mental health and emotional function was not statistically significant (P0.05), the scores were statistically significant (P0.05). After the treatment, test in the group of mental health and emotional function score compared with before treatment there was no statistically significant difference (P0.05), the rest were higher than before treatment (P0.05), the control group in addition to physical pain, mental health and emotional function score compared with before treatment there was no significant difference Significance (P0.05), the rest were higher than before treatment (P0.05) clinical outcome in patients with.3.COPD report (COPD-PRO) before treatment, two groups of patients with clinical symptom score, curative effect satisfaction score, health satisfaction score and COPD-PRO total score was not statistically significant (P0.05). After treatment, scores of the two groups of the field there was statistical significance (P0.05). After treatment, the group test score decreased significantly (P0.01), the control group in addition to health satisfaction score than before treatment had no significant difference (P0.05) score, the rest of the field was decreased compared with that before treatment (P0.05) curative effect satisfaction in patients with.4. (ESQ-COPD) before treatment., two groups of clinical symptom score, curative effect score, overall efficacy score, no significant difference between the work life ability score and ESQ-COPD total score (P0.05). After treatment, scores of the two groups in these areas were statistically difference ISO (P0.05). After the treatment group test score in each of these areas is significantly higher than that before treatment (P0.01), the control group except the difference between clinical symptom score score before treatment were not statistically significant (P0.05) score, the rest of the field increased compared with before treatment (P0.05). In the treatment of convenient score, before and after treatment and the comparison between the two groups before and after treatment in the two groups were not statistically significant (P0.05) between the two groups had no statistically significant skin sensitization treatment induced skin sensitivity evaluation.5. (P0.05). The experimental group has 2 patients appeared obvious erythema in skin during 1 months of treatment, the score is equal to 2 for the determination of sensitization positive; during the 3 months of treatment 4 cases of patients with positive skin sensitization, 1 cases showed mild erythema and slight edema, the other 3 cases showed obvious erythema. Experimental group after treatment were 6 cases of patients with positive skin sensitization, allergic sensitization rate was 4%, grade genus Grade I, sensitized with weak intensity. The control group without Yifei moxibustion treatment. Conclusion: 1 Yifei moxibustion therapy can improve clinical symptoms of patients with stable COPD, improve the daily life and communication ability, the quality of life of patients with improved.2 Yifei moxibustion therapy can improve the curative effect, has certain improvement.3 Yifei moxibustion in the treatment of skin sensitization effect on the strength of weak patient satisfaction, the occurrence of skin sensitization rate is low.

【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.1

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