健步通脉方治疗寒凝血瘀型下肢动脉硬化闭塞症临床观察及红外热像图对比分析

发布时间：2018-01-01 21:35

本文关键词：健步通脉方治疗寒凝血瘀型下肢动脉硬化闭塞症临床观察及红外热像图对比分析　出处：《黑龙江中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：本课题从临床观察角度采用健步通脉方(自拟方药)治疗早期寒凝血瘀型下肢ASO患者,通过测定记录治疗前后两组患者临床症状和体征的改善情况、患肢ABI指数,对比分析两组患者患肢不同部位红外热图温度的变化,评价健步通脉方对早期下肢ASO(寒凝血瘀型)患者的临床疗效,为治疗寒凝血瘀型下肢动脉硬化闭塞症提供新的治疗药物,并对下肢ASO的诊断和临床症状的评估提供新的手段。方法：本研究选取2015年1月-2015年11月我院周围血管病科符合纳入标准的下肢ASO门诊患者。两组患者共60例(76条患肢),男性45例,女性15例,年龄40-69岁,平均57.63岁,病程1-2年,平均15.05月。将所有研究对象按就诊先后顺序分为2组,每组各30例患者,治疗组患肢39条、对照组患肢37条,治疗时间为12周。治疗组患者应用健步通脉方冲剂治疗。对照组患者采用通塞脉片口服治疗。对治疗12周后两组患者的总体疗效、临床症状及体征、ABI值等进行对照分析,同时观察治疗前后红外热像图温度的变化。结果：(1)疗程结束后,治疗组总有效率为96.67%,对照组总有效率93.33%,治疗组疗效优于对照组,P0.05,统计学差异显著。(2)治疗后治疗组患者的皮肤发凉、肢体酸胀、肢体麻木、间歇性跛行、皮温降低、肤色异常情况的改善程度优于对照组,与对照组比较差异有显著性,P0.05。(3)治疗后治疗组患者的大腿、小腿、足背、足趾、足底温度提升明显高于对照组,P0.05,差异具有统计学意义。结论：1、健步通脉方对早期寒凝血瘀型下肢动脉硬化闭塞症患者的治疗优于通塞脉片,疗效作用显著。2、红外热像仪技术对于下肢动脉硬化闭塞症的诊断及疗效评估有一定的提示作用。
[Abstract]:Objective: this topic from the viewpoint of clinical observation by vigorous Tongmai Decoction (decoction medicine) early treatment of cold coagulation and blood stasis in patients with lower extremity ASO, through the improvement of measurement and record two groups of patients with clinical symptoms and signs before and after the treatment, limb ABI index, comparative analysis of two groups of patients with limb position does not change with the temperature of infrared thermography vigorous, evaluation of Tongmai Recipe on early lower extremity ASO (cold coagulation and blood stasis) clinical curative effect of the patients, for the treatment of lower limb arteriosclerosis obliterans with cold coagulation and Blood Stasis Treatment of new drugs, and to assess the clinical symptoms and diagnosis of lower extremity ASO provide new means. Methods: This study selected from January 2015 -2015 November hospital oblitera.ns met the inclusion criteria of lower extremity in patients with ASO. Two groups of patients with a total of 60 cases (76 limbs), 45 males and 15 females, aged 40-69 years old, average 57.63 years old, duration 1-2 years, average 15.05 months. All the studies will be The subjects were divided into 2 groups according to the sequence of treatment, 30 patients in each group, the treatment group 39 limbs, 37 limbs in control group, the treatment time was 12 weeks. The patients in the treatment group were used with Tongmai Granules Treatment. The control group was treated with Tongsaimai Tablets for oral treatment. The overall efficacy of the two groups of patients after 12 weeks of treatment, the clinical symptoms and signs, such as the value of ABI were analyzed, and the temperature changes of infrared thermography observed before and after treatment. Results: (1) after the end of treatment, the total efficiency of treatment group was 96.67%, control group total effectiveness 93.33%, the treatment group than the control group, P0.05, statistically significant difference (2). The patients in the treatment group after treatment of skin cold, limb soreness, numbness, intermittent claudication, decreased skin temperature, skin abnormalities much better than the control group, there was significant difference compared with the control group, P0.05. (3) patients in the treatment group after treatment of thigh, calf, The back of the foot and toe, foot temperature increase significantly higher than the control group, P0.05, the difference was statistically significant. Conclusion: 1, with Tongmai Decoction on early cold coagulation and blood stasis in treatment of lower extremity arterial occlusive disease patients is better than that of Tongsaimai Tablets. The curative effect was.2, infrared thermography technology has certain implications for lower extremity artery occlusive disease diagnosis and curative effect evaluation.

【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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