中医药对吸烟所致冠状动脉内皮损伤的干预作用研究

发布时间：2018-01-01 22:15

本文关键词：中医药对吸烟所致冠状动脉内皮损伤的干预作用研究　出处：《亚太传统医药》2017年06期 　论文类型：期刊论文

更多相关文章：吸烟 内皮损伤 中医药干预 内皮素- NO

【摘要】：目的:通过观察通脉1号方水丸对吸烟患者血管内皮损伤的影响,为改善吸烟者血管内皮功能提供中医药干预的新策略。方法:将行冠脉CT证实为存在冠状动脉粥样硬化且中医辨证为热毒血瘀证120例吸烟者随机分为对照组与治疗组各60例,对照组患者给予常规治疗,治疗组在常规治疗的基础上采用中药水丸口服,治疗3个月。观察两组患者治疗前后内皮素-1(ET-1)、NO指标的变化。结果:两组患者治疗前后ET-1指标差异具有统计学意义(P0.05),NO指标结果差异具有显著统计学意义(P0.01)。结论:中医药干预可改善热毒血瘀型吸烟患者的冠状动脉血管内皮功能。
[Abstract]:Objective: to observe the effect of Tongmai No. 1 Fang Shui Pill on vascular endothelial injury in smoking patients. To improve the vascular endothelial function of smokers to provide a new strategy of Chinese medicine intervention. Methods:. 120 smokers were randomly divided into control group (n = 60) and treatment group (n = 60). The patients in the control group were treated with routine therapy, and the patients in the treatment group were treated with traditional Chinese medicine water pill for 3 months on the basis of routine treatment. The endothelin-1 ET-1 was observed before and after treatment in both groups. Results: there was significant difference in ET-1 between the two groups before and after treatment (P 0.05). Conclusion: Chinese medicine intervention can improve the endothelial function of coronary artery in smoking patients with heat toxin and blood stasis type.
【作者单位】：栖霞市中医医院;
【分类号】：R259
【正文快照】： 吸烟是诸多疾病的危险因素,据全球流行病学显示,中国是世界烟草大国,当前有3亿烟民,香烟消费量约为全球总量的三分之一[1]。众所周知,吸烟会引起呼吸系统疾病的产生与恶化,但对心血管系统疾病的推动却鲜为人知,有研究[2]显示,吸烟可加重动脉硬化,降低斑块稳定性,无疑可诱发并

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