基于中医传承辅助平台的叶天士和薛生白治疗湿热性病证用药异同研究

发布时间：2018-01-02 02:20

本文关键词：基于中医传承辅助平台的叶天士和薛生白治疗湿热性病证用药异同研究　出处：《北京中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:(1)通过整理叶天士、薛生白治疗湿热类病证的方剂,研究叶天士、薛生白治疗温病的经验和方法。(2)通过中医传承辅助平台进行数据挖掘,分析叶天士、薛生白治疗湿热类病证的用药规律,对比其异同点,对临床治疗湿热类疾病提供参考。方法:本课题收集整理清代温病大师叶天士、薛生白治疗湿热类病证的方剂,建立方剂数据库。运用中医传承辅助平台软件,挖掘叶天士、薛生白在治疗外感和内伤湿热类病证方剂中的药物使用规律。挖掘出的结果,以一维频次表和二维网络图呈现,从不同角度显示挖掘对象在文献数据集中的分布,以分析总结叶天士、薛生白治疗湿热类病证的临床经验和常用方药。结果:叶天士和薛生白在治疗外感和内伤湿热性病证时,选用药物的四气、五味、归经基本一致,单味药物选用也基本相同,但单味药物使用和选用常用药物组合各有特色。治疗外感湿热类病证时,叶天士以杏仁为核心药物,较多使用利水渗湿的茯苓、泽泻、通草、猪苓、薏苡仁,辛凉清热的生石膏、芦根;药物组合则喜用杏仁-薏苡仁、杏仁-厚朴、杏仁-滑石、杏仁-竹叶组合,形成三仁汤的雏形。薛生白选用芳香化湿的厚朴、草果、藿香、白豆蔻,淡寒的滑石和辛凉透热的金银花和连翘;药物组合则喜用厚朴-陈皮-茯苓皮、滑石-甘草组合。治疗内伤湿热类病证时,叶天士使用利水渗湿的茯苓、猪苓、泽泻、通草、滑石,清热燥湿的黄芩、黄连、黄柏和清热泻火的竹叶,药物组合喜用茯苓-猪苓-泽泻组合加上陈皮-厚朴组合可看作是四苓散的加减。薛生白则选用芳香化湿的厚朴、草果、藿香、白豆蔻,清热祛湿药物木通、茵陈等;理气药物组合喜用厚朴-陈皮-草果、厚朴-陈皮-藿香、厚朴-杏仁-白豆蔻组合,仿吴又可达原饮。结论:叶天士和薛生白在治疗外感和内伤湿热性病证时,选用药物的四气、五味、归经基本一致,单味药物选用也基本相同,常用药物组合都选用了陈皮-厚朴。在治疗外感湿热类病证时,叶天士突出以杏仁为核心,使用杏仁-半夏-生姜、杏仁-防己-薏苡仁、杏仁-半夏-厚朴、杏仁-滑石-竹叶等药物组合;治疗内伤湿热类病证时突出以茯苓为核心,使用茯苓-猪苓-泽泻、茯苓-白术、茯苓-人参、茯苓-陈皮-厚朴等药物组合。薛生白则在治疗外感和内伤湿热性病证时皆以陈皮、厚朴为核心药物,治疗外感湿热类病证时亦常用滑石-甘草的六一散组合,并喜用草果、藿香等芳化湿浊的药物,治疗内伤湿热类病证时常用药物组合是在陈皮-厚朴组合基础上添加为陈皮-厚朴-草果、陈皮-厚朴-藿香、陈皮-厚朴-茯苓皮,此外厚朴-杏仁-白豆蔻组合亦为常用药物组合。故治疗湿热病时,叶天士使用苦辛寒法的治疗方法,薛生白则使用苦辛温的治疗方法。
[Abstract]:Objective: to study the experience and methods of Ye Tianshi and Xue Shengbai in treating febrile disease by sorting out the prescriptions of Ye Tianshi and Xue Shengbai for treating damp-heat diseases. Analysis of Ye Tianshi Xue Shengbai treatment of damp-heat type of disease drug law compare its similarities and differences to provide a reference for clinical treatment of damp-heat diseases. Methods: this topic collected and sorted out the Qing Dynasty febrile disease master Ye Tianshi. Xue Shengbai treatment of damp-heat type of disease prescription, the establishment of prescription database. Use of traditional Chinese medicine inheritance platform software, mining Ye Tianshi. Xue Shengbai in the treatment of exogenous and internal injury of damp-heat diseases in the prescription of drug use. Excavated results, presented by one-dimensional frequency table and two-dimensional network diagram. The distribution of mining objects in the literature data set is shown from different angles to analyze and sum up Yetix. Xue Shengbai's clinical experience and common prescriptions in treating damp-heat type disease syndrome. Results: Ye Tianshi and Xue Shengbai chose the four qi and five flavors of medicine when treating external and internal injury damp-heat venereal disease syndrome. Single drug selection is basically the same, but single drug use and use of common drug combinations have their own characteristics. In the treatment of exogenous dampness and fever syndrome, Ye Tianshi to almond as the core drug, more use of water and infiltration of Poria cocos. Rhizoma alisma, Tungcao, Polyporus umbellata, Coix seed, Xin Liang Qinghot raw gypsum, Reed root; The combination of almond-Coix seed, almond-magnolia, almond-talc, almond and bamboo leaves formed the embryonic form of Sanren decoction. Xue Shengbai chose aromatization of Magnolia officinalis, grass fruit, patchouli and cardamom. Cold talc and chilled honeysuckle and forsythia; When treating dampness and heat syndrome of internal injury, Ye Tianshi used Poria cocos, Polyporus umbellata, alisma, purses, herbs, talc, and Scutellaria baicalensis. Rhizoma Coptidis, Phellodendron chinensis and bamboo leaves with clear heat and purging fire, medicine combination likes to use Poria cocos-Polyporus umbellata combination plus Chen Pei-Magnolia officinalis combination can be regarded as the addition or subtraction of Siling San. Xue Shengbai chooses the aromatization of Magnolia officinalis, grass fruit, and patchouli. White nutmeg, clearing heat and removing dampness medicine Akebia, Yinchen and so on; Li-qi medicine combination prefer to use Magnolia officinalis-old peel-grass fruit, Magnolia-Chenpi-patchouli, Magnolia-almond-white nutmeg combination. Conclusion: Ye Tianshi and Xue Shengbai used the same medicine in treating external and internal injury damp-heat venereal disease syndrome. In the treatment of external dampness-heat disease syndrome, Ye Tianshi prominent almond as the core, using almond-Pinellia ternata-ginger, almond-Fangji-Coix seed, almond-Pinellia ternata-Magnolia officinalis. Almond-talc-bamboo leaves and other drug combinations; In the treatment of damp-heat disease syndrome, the core is Poria cocos, using Poria-Polyporus-Alismatis, Poria cocos-Atractylodes Atractylodes, Poria cocos-Ginseng. Xue Shengbai takes Chen Pei and Magnolia officinalis as the core drug in the treatment of external and internal damp-heat venereal disease syndrome. The combination of talc and licorice is also commonly used when treating external damp-heat syndrome. And like to use herbs, patchouli and other aromatization of dampness and turbid drugs, the treatment of dampness and heat diseases of internal injury commonly used medicine combination is based on the combination of Chen Pei-Magnolia officinalis-grass fruit, old skin-Magnolia-patchouli. Chen Pei-Magnolia officinalis-Poria cocos, in addition, Magnolia officinalis-Almond-White nutmeg combination is also a common drug combination. Therefore, in the treatment of damp-heat disease, Yetianshi uses bitter and bitter cold treatment method, Xue Shengbai uses bitter and warm treatment method.
【学位授予单位】：北京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R254

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