光声成像在腧穴微循环敏化成像研究中的应用展望

发布时间：2018-01-02 05:12

本文关键词：光声成像在腧穴微循环敏化成像研究中的应用展望　出处：《针刺研究》2017年05期 　论文类型：期刊论文

【摘要】：当前腧穴敏化的成像研究相对不足,尤其在组织微循环层次上难以深入。光声成像具备高对比度、高探测深度、对组织功能特性敏感等特点,是微循环成像领域的主流技术与前沿热点之一。本文简要介绍了光声成像,并从结构及功能方面综述了微循环的光声成像研究进展。光声成像能够对兴趣组织一定深度范围内的微循环结构进行3D、高空间分辨率成像及量化评价,同时能够对目标血管的总血红蛋白浓度及其氧合水平、血流速、氧代谢水平、微血管舒缩运动、血流动力学等进行实时、动态监测。在此基础上,本文结合当前腧穴微循环敏化的成像研究进展,展望了光声成像在腧穴微循环敏化成像研究中的应用。光声成像与腧穴敏化成像研究的实际需要相符合,在敏化态腧穴局部微循环与腧穴的中枢敏化成像上具有应用潜力,有望进一步明确敏化态腧穴微循环的特征性改变,丰富腧穴中枢敏化的具体内涵。
[Abstract]:At present, the study of acupoint sensitization imaging is relatively insufficient, especially in the tissue microcirculation level is difficult to go deep. Photoacoustic imaging has the characteristics of high contrast, high detection depth, sensitive to tissue functional characteristics and so on. It is one of the mainstream technologies and hot spots in the field of microcirculatory imaging. In this paper, photoacoustic imaging is briefly introduced. The research progress of photoacoustic imaging of microcirculation is reviewed in terms of structure and function. Photoacoustic imaging can be used for 3D, high spatial resolution imaging and quantitative evaluation of microcirculatory structures in a certain depth range of tissue of interest. At the same time, the hemoglobin concentration and oxygenation level, blood flow velocity, oxygen metabolism level, microvascular movement, hemodynamics and so on can be monitored in real time and dynamically. In this paper, the application of photoacoustic imaging in the study of acupoint microcirculation sensitization imaging is prospected, which is in line with the actual needs of acupoint sensitization imaging research in combination with the current research progress of acupoint microcirculation sensitization imaging. It has the potential to be applied in the local microcirculation of sensitized acupoints and the central sensitization imaging of acupoints, which is expected to further clarify the characteristic changes of the microcirculation of sensitized acupoints and enrich the specific connotation of the central sensitization of acupoints.
【作者单位】：北京中医药大学针灸推拿学院;北京中医药大学护理学院;
【基金】：国家自然科学基金重大项目(No.81590952)
【分类号】：R245-3
【正文快照】： 腧穴敏化是指在病理状态下,腧穴从“沉寂”到“激活”的动态转化过程,涉及局部有关组织、细胞、分子等一系列变化。在组织层面,微循环作为人体脏器的重要构成及循环系统的最小分支与功能单元,在物质供应与代谢、维持血流灌注及内环境稳定等方面发挥关键作用[1],与腧穴敏化密切

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