基于数据挖掘治疗肾虚型月经病的用药分析

发布时间：2018-01-02 10:03

本文关键词：基于数据挖掘治疗肾虚型月经病的用药分析　出处：《中国实验方剂学杂志》2017年15期 　论文类型：期刊论文

【摘要】：目的:探讨南京中医药大学附属医院(江苏省中医院)妇科治疗肾虚型月经病用药规律,为临床治疗及新药研发提供指导。方法:收集江苏省中医院妇科门诊2016年5月到2016年10月治疗肾虚型月经病处方1 075张,利用微软Excel强大的排序、筛选和统计功能进行数据挖掘,统计各中药的用药比例。结果:使用频率在50%以上的单味中药有续断、茯苓、白芍(炒)、山药、丹参、山茱萸(酒)、赤芍、菟丝子8种。使用频率在30%~50%的中药有当归、白术(麸炒)、香附(醋)、熟地黄、牡丹皮、杜仲(盐)6种。使用频率在10%以上43种中药中,以中药学常规分类,使用率较高的依次是补益药、活血化瘀药,其他为清热药、理气药等。以药性分类,使用率由高到低依次是温性药、平性药及寒性药,温性药的使用率显著高于平性药、寒性药。药对使用以茯苓-山药为最高(51.2%),其次是山药-山茱萸(47.7%),白芍-赤芍(39.5%)等。结论:我院妇科治疗肾虚型月经病擅用续断、茯苓、白芍(炒)、山药、丹参、山茱萸(酒)、赤芍、菟丝子等单味药,药对则以茯苓-山药,山药-山茱萸,白芍-赤芍应用见长。这些药物的应用充分体现了补益、健脾、活血、祛寒的治法治则,反映了治疗肾虚型月经病的用药规律。
[Abstract]:Objective: To investigate the Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Province Traditional Chinese Medicine Hospital) regular medication kidney menstruation treatment of gynecological diseases, and provide guidance for clinical treatment and drug development. Methods: from May 2016 to October 2016 in Jiangsu Province Traditional Chinese Medicine Hospital outpatient treatment of kidney deficiency type menstrual disease prescription 1075, using Microsoft Excel powerful sorting, selection and statistical functions of data mining, the statistics of Chinese medicine the proportion of treatment. Results: the frequency of use in more than 50% single herbs have Radix dipsaci, Poria, radix paeoniae alba (fried), yam, radix salviae miltiorrhizae, Fructus Corni (wine), red peony, dodder 8. Use frequency in 30%~50% traditional Chinese medicine angelica, Atractylodes (fried gluten), Rhizoma Cyperi, Radix Rehmanniae Preparata (vinegar) Moutan, eucommia, (salt) 6. Use frequency in more than 10% of the 43 kinds of traditional Chinese medicine, pharmacy in conventional classification, followed by a high rate of use of tonic, blood stasis and other antipyretic drugs. Drug, Qi The classification, use rate from high to low is the temperature of the medicine, medicine and flat cold medicine, use warm medicine was significantly higher than that of flat medicine, cold medicine. The use of medicine to Fuling - yam was the highest (51.2%), followed by yam - dogwood, radix paeoniae alba (47.7%) - Red Peony (39.5%). Conclusion: our hospital treatment of kidney deficiency type of menstrual disorders using Radix dipsaci, Poria, radix paeoniae alba (fried), yam, radix salviae miltiorrhizae, Fructus Corni (wine), red peony root, dodder and other herbs, medicine of in - Poria yam, yam, Cornus alba, Radix Paeoniae Rubra Kyo - application the application of these drugs. Fully embodies the invigorating spleen, promoting blood circulation, and cold dispelling rule, reflects the medication rule of treatment of kidney deficiency type menstrual disease.

【作者单位】：南京中医药大学附属医院;南京中医药大学药学院江苏省中药药效与安全性评价重点实验室;
【基金】：江苏省高校优势学科建设工程项目(中药学) 南京药学会常州四药医院药学科研基金项目(2015YX010)
【分类号】：R271.11
【正文快照】： 2.南京中医药大学药学院,江苏省中药药效与安全性评价重点实验室,南京210023)[网络出版地址]http://kns.cnki.net/kcms/detail/11.3495.R.20170511.0906.020.html[网络出版时间]2017-05-11 9:06月经病是以月经周期、经期或经量发生异常,或以伴随月经周期出现的各种症状为特征,

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