老年高血压与中青年高血压中医治法及用药规律文献研究

发布时间：2018-01-03 04:18

本文关键词：老年高血压与中青年高血压中医治法及用药规律文献研究　出处：《中医杂志》2017年14期 　论文类型：期刊论文

【摘要】：目的探析老年高血压和中青年高血压中医治法和用药规律并比较二者的异同。方法纳入中国知网、万方数据知识服务平台、维普数据库中中医药治疗老年高血压和中青年高血压的临床研究,提取治法和用药信息建立处方数据库,并对数据进行频次、频率统计和聚类分析。结果共纳入老年高血压文献161篇,中青年高血压文献40篇。涉及中医治法16种,其中老年高血压中医治法频次在前4位的是活血(77)、滋养肝肾(68)、平肝潜阳(67)、益气(47);中青年高血压中医治法频次在前4位的是平肝潜阳(21)、清肝泻火(18)、活血(15)、化痰降浊(15)。治疗老年高血压相关方剂195首,涉及中药181味,频次最高的前10位依次是牛膝、茯苓、天麻、丹参、当归、钩藤、川芎、黄芪、泽泻、甘草;治疗中青年高血压相关方剂53首,涉及中药115味,频次最高的前10位依次是钩藤、茯苓、白芍、天麻、白术、黄芩、菊花、牛膝、石决明、泽泻。聚类分析结果显示,治疗老年高血压存在5个核心药物群,治疗中青年高血压存在7个核心药物群。结论老年高血压和中青年高血压在治法和用药上都强调平肝潜阳、活血,其中前者侧重于益气养血、补益肝肾,兼顾利湿化痰、凉肝熄风;后者则偏重于清热泻火、化痰降浊,同时兼顾滋阴潜阳、疏肝调脾。
[Abstract]:Objective to explore the law of TCM treatment and medication of hypertension in the elderly and young people and compare their similarities and differences. The clinical study of traditional Chinese medicine in the treatment of hypertension in the elderly and young people in Weipu database. The prescription database was established by extracting the treatment method and medication information, and the frequency of the data was carried out. Frequency statistics and cluster analysis. Results A total of 161 papers on hypertension in the elderly and 40 articles on hypertension in the young and middle-aged were included, involving 16 kinds of TCM treatment methods. Among them, in the first four times of TCM treatment frequency of senile hypertension is promoting blood circulation, nourishing the liver and kidney, nourishing the liver and kidney, calming the liver and burying the yang, benefiting the qi and removing the sun, and nourishing the qi. In the first four times of the treatment of hypertension in the young and middle-aged, the first four were Pinggan Qianyang, Qinggan Xiuhuo 18N, Huoxuejiu 15jiao, Huatan Jiangzhuo 15N. 195 related prescriptions for treating senile hypertension were selected. Involving 181 kinds of Chinese medicine, the top 10 of the highest frequency are Achyranthes bidentata, Poria cocos, Gastrodia elata, Salvia miltiorrhiza, Radix angelicae sinensis, Rhizoma Ligusticum Chuanxiong, Astragalus membranaceus, Rhizoma Alism@@. Treatment of young and young people with hypertension related prescriptions 53, involving 115 Chinese medicine, the highest frequency of the top 10 is hookwood, Poria cocos, white peony, Gastrodia, Atractylodes macrocephala, Scutellaria baicalensis, chrysanthemum, Achyranthes bidentata, stone cassia. The results of cluster analysis showed that there were five core drug groups in the treatment of elderly hypertension. There are seven core drug groups in the treatment of middle and young hypertension. Conclusion elderly hypertension and young hypertension both emphasize calming the liver and latent yang and activating blood circulation in the treatment of hypertension. The former emphasizes on nourishing qi and nourishing blood and tonifying liver and kidney. Taking into account the benefits of dampness and phlegm, cooling the liver to quell the wind; The latter focuses on clearing away heat and reducing fire, eliminating phlegm and reducing turbid, simultaneously taking into account the nourishing yin and burying yang, soothing the liver and regulating the spleen.
【作者单位】：天津中医药大学;天津中医药大学第一附属医院;
【基金】：国家中医药管理局国家中医临床研究基地业务建设科研专项(JDZX2015148)
【分类号】：R259
【正文快照】： 高血压病是目前威胁人类健康的重要疾病之一,随着年龄的增长其患病率逐渐升高,血压控制达标率亦随之下降,与此同时主要心血管事件发生的绝对风险也随之显著增加[1]。因此,根据不同年龄高血压病的发病特点,有针对性地进行治疗,是提高临床疗效的重要策略。为了更好地发挥中医药

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