调肝降压方对高血压肝火亢盛证患者生存质量的影响

发布时间：2018-01-03 06:09

本文关键词：调肝降压方对高血压肝火亢盛证患者生存质量的影响　出处：《山东中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:本研究旨在采用高血压生存质量量表评价调肝降压方治疗高血压肝火亢盛证患者的临床疗效。方法:选择符合标准的高血压肝火亢盛证患者60例,采用分层随机化方法分为试验组和对照组,各组30例。试验组给予调肝降压方联用规范化抗高血压治疗方案,对照组给予单纯规范化抗高血压治疗方案,研究分为导入期、随机化治疗期。分别观察治疗前后的血压、中医证候及生存质量。结果:1.降压疗效:对照组降压总有效率85.19%,试验组为89.66%,组间无显著性差异(P0.05)。降压幅度:治疗后两组血压水平均较治疗前显著降低(P0.01)。两组间SeSBP、SeDBP降压幅度比较均无显著性差异(P0.05),PP降低幅度比较,组间有显著性差异(P0.05)。2.中医证候疗效:对照组中医证候的总有效率70.37%;试验组为93.10%,组间有显著性差异(P0.05)。中医证候积分:治疗后两组中医证候积分与治疗前相比明显降低(P0.01);两组间中医证候积分差值比较有显著性差异(P0.05)3.生存质量:两组生理症状、躯体化症状、睡眠状况、生气或活力、强迫、工作状态治疗前后比较,差异有显著性(P0.01),两组间躯体化症状、性功能、睡眠状况、生气或活力、工作状态治疗前后差值比较有显著性意义(P0.05~P0.01)。结论:调肝降压方联用规范化抗高血压治疗方案在缩小PP、改善中医证候、提高生存质量方面具有明显疗效。
[Abstract]:Objective: the purpose of this study is to use the clinical curative effect of hypertension quality of life scale evaluation of adjusting liver antihypertensive treatment in hypertensive patients with hyperactivity of liver fire syndrome. Methods: choose the standard of hypertension liver fire hyperactivity syndrome in 60 cases, stratified randomization were divided into experimental group and control group, 30 cases in each group. The experimental group was given adjusting liver antihypertensive combined with standardized antihypertensive therapy, the control group was treated with standardized antihypertensive therapy, the research is divided into introduction, random treatment period. Before and after treatment were observed in blood pressure, symptoms and quality of life of TCM syndrome. Results: 1. antihypertensive effect: the control group the total efficiency of 85.19%, the test group was 89.66%. There was no significant difference between groups (P0.05). Blood pressure increase after treatment, blood pressure levels in the two groups were significantly lower than those before treatment (P0.01). Among the two groups SeSBP, SeDBP step-down amplitude comparison showed no significant difference (P0.05), PP amplitude decreased The degree of comparison, there are significant differences between the groups (P0.05.2.) TCM syndrome curative effect: the total effective rate was 70.37% in control group syndrome; experimental group was 93.10%, there were significant differences between the groups (P0.05). TCM syndrome score: two groups after treatment of TCM syndrome integral was significantly reduced compared with before treatment between the two groups (P0.01); TCM syndrome score difference was significant difference (P0.05 3.) quality of life: two groups of physical symptoms, somatic symptoms, sleep status, anger or vigor, force, working condition before and after treatment, there were significant differences between the two groups (P0.01), somatic symptoms, sex function, sleep, anger or vigor, working state before and after the treatment difference was statistically significant (P0.05~P0.01). Conclusion: adjusting liver antihypertensive combined with standardized antihypertensive therapy in reducing PP, improve the TCM syndrome, has obvious curative effect to improve the quality of life.

【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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