针刺联合贴脐法防治铂类化疗所致迟发性呕吐的临床疗效评价

发布时间：2018-01-04 04:17

本文关键词：针刺联合贴脐法防治铂类化疗所致迟发性呕吐的临床疗效评价　出处：《浙江中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的明确针刺联合贴脐法对铂类化疗所致迟发性呕吐的预防和治疗作用。方法:将64例符合纳入标准的化疗后迟发性呕吐患者随机分为观察组和对照组各32例。对照组采用常规西药治疗给予格拉司琼和地塞米松,观察组在对照组的基础上采用针刺联合贴脐法,穴选内关、公孙、足三里,中脘、神阙,贴脐药粉由半夏和生姜按比例调配而成。在治疗第2天、治疗第5天对所有患者进行MASCC止吐工具量表评分;治疗前,治疗第2天、治疗第5天进行卡氏评分指数评分,观察患者的患者生存状况和体力情况的变化以及总体疗效。结果1.在治疗第2天,观察组在呕吐次数及恶心程度改善方面均优于对照组(P0.05)。2.与治疗第二天比较,治疗第5天两组呕吐次数及恶心程度均减少明显(P0.05),并且治疗组优于对照组(P0.05);与治疗第2天相比,治疗组的卡氏评分显著升高(P0.05),并且治疗组在改善生存状况和体力情况上优于对照组(P0.01)。3.治疗5天后观察组和对照组总有效率分别为93.75%和75%(P0.05)。结论针刺联合贴脐法治疗化疗后迟发性呕吐能改善患者的恶心呕吐症状,改善患者的生活活动能力,提高患者的生存质量。
[Abstract]:Objective to investigate the preventive and therapeutic effects of acupuncture combined with umbilical patch on delayed vomiting induced by platinum chemotherapy. Sixty-four patients with delayed vomiting after chemotherapy were randomly divided into observation group (n = 32) and control group (n = 32). The control group was treated with granisetron and dexamethasone. On the basis of the control group, acupuncture combined with navel sticking method was used in the observation group. The points were selected from Neiguan, Gongsun, Zusanli, Zhongwan, Shenque, paste umbilical powder from Pinellia ternata and ginger on the second day of treatment. On the 5th day of treatment, all patients were evaluated with MASCC instrument scale. Before treatment, the second day of treatment and the fifth day of treatment, the Karnox score index score was performed to observe the changes of patients' living condition and physical strength, as well as the overall curative effect. Results 1. On the second day of treatment. 2. The number of vomiting and the improvement of nausea in the observation group were better than those in the control group (P0.050.2.), compared with the second day of treatment. On the 5th day, the number of vomiting and the degree of nausea in the two groups were significantly decreased, and the treatment group was better than the control group. Compared with the second day of treatment, the treatment group had a significantly higher Karnoff score (P0.05). After 5 days of treatment, the total effective rates of the observation group and the control group were 93.75% and 75 respectively. Conclusion Acupuncture combined with umbilical patch can improve the symptoms of nausea and vomiting in patients with delayed vomiting after chemotherapy. Improve patients' ability to live and improve their quality of life.
【学位授予单位】：浙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R246.5

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