电针结合激光治疗肥胖型多囊卵巢综合征的临床疗效观察

发布时间：2018-01-05 12:13

本文关键词：电针结合激光治疗肥胖型多囊卵巢综合征的临床疗效观察　出处：《南京中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：通过观察电针结合激光治疗肥胖型多囊卵巢综合征的临床疗效,探讨其疗效机理,并为今后联合运用电针结合激光治疗肥胖型多囊卵巢综合征提供参考依据。方法：将70例符合纳入标准的肥胖型多囊卵巢综合征患者随机分为电针组、电针结合激光组(光电组),各35例。治疗3个月后,分别观察两组治疗前后中医症状评分及证候疗效、月经周期、体重、体重指数(BMI)、减重疗效、黄体生成激素(LH)、LH/FSH、睾酮(T)、空腹血糖(FPG)、空腹胰岛素(FINS)、胰岛素抵抗水平(HOMA-IR)等指标的变化,比较两种方法的临床疗效。结果：临床共收集符合纳入标准的受试者70例,6例脱落,其余64例纳入结果进行分析。治疗前,两组在各项观察指标方面无统计学差异,两组之间具有可比性。(1)中医症状评分及证候疗效：经过治疗,两组中医症状评分均显著下降,且有显著性差异(P0.01)；治疗后两组之间比较,光电组治疗后中医症状评分较电针组低,差异有统计学意义(P0.05),且治疗后光电组总有效率84.38%,电针组总有效率78.13%,光电组在改善中医证候的疗效上优于单纯电针组(P0.05)；(2)月经周期变化：两组月经周期在治疗后均显著缩短(P0.01),且治疗后光电组月经周期缩短疗效优于电针组(P0.05);(3)体重、BMI及减重疗效：两组治疗后,体重及BMI均显著下降,差别具有统计意义(P0.05)；治疗后两组在降低受试者体重及BMI上无显著差异(P0.05)；光电组治疗后减重有效率高于电针组,但两组间无统计学差异(P0.05)；(4)性激素变化：两组治疗后性激素水平均下降明显(P0.01)；治疗后比较,LH、LH/FSH的下降程度光电组较电针组明显(P0.05),T的下降程度光电组较电针组显著(P0.01),光电组受试者性激素水平的下降疗效优于电针组；(5)胰岛素抵抗改善情况：治疗后两组FINS、FPG及HOMA-IR均显著下降,有显著性差异(P0.01)。治疗后两组间FINS、FPG及HOMA-IR相比,差别无统计意义(P0.05)。结论： (1)电针、电针结合激光都是治疗PCOS的有效方法； (2)电针结合激光治疗在调整肥胖型PCOS患者月经周期、改善中医症状、性激素等方面疗效均优于单纯电针治疗； (3)激光输出头放置于卵巢局部穴位,从而对卵巢产生良性调节可能是电针结合激光治疗在调整肥胖型PCOS患者月经周期、改善中医证候、性激素等方面疗效优于单纯电针的原因。
[Abstract]:Objective: To observe the clinical curative effect of electroacupuncture combined with laser therapy for the treatment of obesity type polycystic ovary syndrome, and to explore its mechanism, and for the future combination of electro acupuncture and laser treatment of obesity type polycystic ovary syndrome and provide reference basis. Methods: 70 patients met the inclusion criteria of obese patients with polycystic ovary syndrome were randomly divided into electroacupuncture group, electro acupuncture and laser group (group A), 35 cases in each group. After 3 months of treatment were observed in two groups before and after treatment of TCM symptoms and syndromes, menstrual cycle, body weight, body mass index (BMI), weight loss effect, luteinizing hormone (LH), LH/FSH, testosterone (T), fasting blood glucose (FPG), fasting insulin (FINS), the level of insulin resistance (HOMA-IR) and other indicators of change, to compare the clinical efficacy of the two methods. Results: the clinical total of 70 subjects were collected according to the inclusion criteria, 6 cases of falling off, the remaining 64 cases were analyzed . before treatment, no significant difference between the two groups in the observation index, comparable between the two groups. (1) and symptom scores of TCM syndrome curative effect: after treatment, two groups of TCM symptom score decreased significantly, and there is a significant difference (P0.01); after treatment between the two groups were compared, photoelectric after treatment, the TCM symptom score compared with EA group, the difference was statistically significant (P0.05), and after treatment, the total efficiency of 84.38% optical group electroacupuncture group, the total efficiency of 78.13%, the effect of photoelectric group in improving TCM syndrome is superior to simple acupuncture group (P0.05); (2) the variation of the menstrual cycle: two menstruation cycle shortened significantly after treatment (P0.01), and after treatment, the menstrual cycle shortened photoelectric group curative effect is better than that of electroacupuncture group (P0.05); (3) weight, the efficacy of BMI and weight: two groups after treatment, body weight and BMI were significantly decreased, the difference has statistical significance (P0.05); the two groups after treatment in reducing by The subjects had no significant difference in body weight and BMI (P0.05); photoelectric group after treatment, weight loss rate is higher than the effective acupuncture group, but no significant difference between the two groups (P0.05); (4) the sex hormone changes: after treatment of the two groups of sex hormone levels were decreased significantly (P0.01); after treatment, LH, LH/, FSH the decrease of photoelectric group compared with EA group significantly (P0.05), T decreased significantly compared with EA group photoelectric group (P0.01), photoelectric subjects of sex hormone levels decreased efficacy than electroacupuncture group; (5) the improvement of insulin resistance: two groups after treatment FINS, FPG and HOMA-IR were significantly decreased, there is significant differences (P0.01). After treatment between the two groups of FINS, compared to FPG and HOMA-IR, the difference was not statistically significant (P0.05). Conclusion: (1) electro acupuncture, electro acupuncture and laser are effective methods for the treatment of PCOS; (2) electroacupuncture combined with laser therapy in obese PCOS patients to adjust the menstrual cycle, improve TCM symptoms. And exciting Effect of pigment is superior to simple acupuncture therapy; (3) the laser head is placed in the local ovarian points, resulting in benign regulation may be electro acupuncture and laser therapy in the treatment of obese patients with PCOS adjustment of the menstrual cycle on ovary, improve the TCM syndrome, causes of sex hormone and other side effects than simple electroacupuncture.

【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.3

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