复方秦艽片联合黛力新治疗肛门直肠躯体化障碍的疗效观察

发布时间：2018-01-06 16:34

本文关键词：复方秦艽片联合黛力新治疗肛门直肠躯体化障碍的疗效观察　出处：《山东中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:通过观察将复方秦艽片和黛力新结合用药治疗湿热下注型肛门直肠躯体化障碍的临床效果,同单纯口服黛力新的治疗效果相比较,观察两药联合应用的临床疗效,寻求治疗湿热下注型肛门直肠躯体化障碍的最佳方法,及时为湿热下注型肛门直肠躯体化障碍患者减轻痛苦,提高患者的生活幸福指数,为临床施治提供可靠的依据。方法:选取符合肛门直肠躯体化障碍纳入标准的60名患者,时间限定于2014年6月到2015年6月,地点选择在山东省中医院(山东中医药大学附属医院)肛肠科门诊。其中因肛门及肛周疼痛就诊的患者26例,随机选取13人作为试验组,剩余的人作为对照组。因肛门坠胀来看诊的患者34人,随机选取17人作为试验组,剩余人作为对照组。通过用SPSS19.0统计分析,患者的性别、年龄、受教育程度等在对照组和试验组之间无明显差异(P0.05)。试验组患者给予黛力新(氟哌噻吨美利曲辛片,丹麦灵北制药有限公司生产,规格10.5mg/片)口服,每日2次(早、中午),每次10.5mg,同时口服复方秦艽片(山东省中医院自制药)3g(10片),日三次。对照组只服用黛力新,服用方法和试验组一致。以15天为一个治疗阶段,在用药期间,不允许患者摄入辛辣刺激油腻性食品和任何对研究结果可能产生影响的药物。试验开始前、用药30天后,患者分别填写根据症状自评量表(SCL-90)改编的适合本课题研究的量表和SAS量表。试验过程中,患者一旦出现副作用,实时记录并对症处理。研究过程中的所有数据资料应用SPSS19.0软件分析,计量资料用均数士标准差的格式来体现,有明显性差异的标准为P0.05。结果:黛力新结合复方秦艽片医治湿热下注型肛门直肠躯体化障碍总有效率为93.33%,单纯口服黛力新治疗总有效率为56.67%。两组患者均没有出现严重不良反应。两组对比可见:两药联合应用见效快、效果显著、副作用少。故两药联合治疗湿热下注型肛门直肠躯体化障碍具有切合病机,协同互补,功效明显的巨大优势。
[Abstract]:Objective: To observe the clinical effect of compound tablets combined with Deanxit treatment of Gentiana and damp type anorectal somatization disorder, with simple oral Deanxit treatment compared to observe the clinical curative effect of the combination of two drugs, the best method for treatment of damp heat type anorectal somatization disorder in patients with type of damp heat. Anorectal somatization disorder, relieve pain, improve the patients' life happiness index, provide a reliable basis for clinical treatment. Methods: 60 patients with anorectal somatization disorder criteria, time from June 2014 to June 2015, the venue of the Shandong Provincial Traditional Chinese Medical Hospital (the Affiliated Hospital of Shandong University of Traditional Chinese Medicine) anorectal clinic. One in 26 cases. The anus and perianal pain patients, 13 were randomly selected as experimental group, the remaining people as the control group. Because of anus Expansion visit patients with 34 people, 17 people randomly selected as experimental group, the remaining people as the control group. By using SPSS19.0 statistical analysis, gender, age, education level in between the control group and the experimental group had no significant difference (P0.05). The experimental group was treated with Dai Lixin (Flupentixol and Melitracen Tablets, Denmark lundbeck limited production, specifications 10.5mg/) orally, 2 times a day (morning, noon), 10.5mg each time, while oral compound tablets of Gentiana (homemade medicine Shandong Provincial Traditional Chinese Medical Hospital) 3G (10), three times a day. The control group only treated with Diane force new, taking method and the experimental group. In 15 days for a treatment stage, during the treatment, drugs do not allow patients to eat spicy greasy food and stimulate any of the results might be affected. The start of the experiment, after 30 days of treatment, the patients were filled out according to the symptom checklist (SCL-90) adapted for this lesson Research on the scale and SAS scale. During the test, once the patient has side effects, real-time recording and symptomatic treatment. All the data analysis using SPSS19.0 software in the research process, measurement data using mean SD format to reflect, there was significant difference of the standard for P0.05. results: Deanxit combined with compound Gentiana tablets treat damp type anorectal somatization disorder, the total efficiency of 93.33%, treated with Deanxit in the treatment of the total efficiency of 56.67%. of two groups of patients had no serious adverse reactions. Two group comparison shows the combination of two drugs: quick, effective, less side effects. So the two drug combination therapy of damp heat type of anus rectal somatization disorder has to meet pathogenesis, collaboration complementary, huge advantage effect is obvious.

【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R266

【参考文献】