加味益胃汤治疗胃阴不足型痤疮的临床研究

发布时间：2018-01-06 17:07

本文关键词：加味益胃汤治疗胃阴不足型痤疮的临床研究　出处：《山西中医学院》2016年硕士论文　论文类型：学位论文

【摘要】：研究目的本研究通过观察以加味益胃汤为主方,对胃阴不足、虚火上炎型痤疮患者的临床疗效,并与单纯西医药物治疗的疗效进行对比,以探求和发展中医治疗寻常型痤疮的新思路、新方法,将为今后临床实践中痤疮的治疗提供可靠的遣方用药依据,也为痤疮中医药治疗开辟了新的道路。研究方法选择在运城市中医医院(2014年12月-2015年11月)诊断为“粉刺(胃阴不足、虚火上炎型)”,并且符合本实验纳入标准的门诊患者50例,根据这50例患者的就诊时间和治疗意愿,随机分为治疗组和对照组,每组各25例,治疗组给予中药加味益胃汤治疗,中药水煎剂,水煎服,日2次,每日1剂;对照组患者给以维胺酯胶囊,温开水送服,每次50mg,每日两次,饭后半小时服用。疗程4周,对照比较治疗组与对照组的综合疗效,皮损疗效。治疗期间忌食生冷、辛辣等发物,注意保持情绪乐观和良好作息。研究结果治疗4周后两组患者的皮损积分均较前下降,治疗组在治疗前后积分比较T值为18.321,p值0.05,统计学差异明显,说明治疗效果显著;对照组内比较:对照组治疗前后积分比较T值13.086,p值0.05,统计学差异明显,说明治疗效果显著。组间比较:两组在治疗前T值0.514,p值0.05,说明两组疗前积分比较没有统计学意义,差异不明显;治疗2周后,两组积分对比T值为1.741,p值0.05,此时两组积分比较没有统计学意义;治疗4周后,T值0.610,p值0.0020.05,两组积分有显著差异,治疗组皮损疗效积分改善情况高于对照组。两组综合疗效比较,总有效率比较x2值10.068,p值0.05,说明两组对象疗效具有显著差异,治疗组疗效显著好于对照组。结论本课题实验通过治疗组和对照组药物疗效比较,论证了导师自拟加味益胃汤对胃阴虚型痤疮治疗效果的可确定性及治疗的安全性,探讨了中医治疗胃阴虚型痤疮的特点和可行性,说明中医在痤疮的长期治疗中有很大的优势,值得人们探讨和推广。
[Abstract]:Objective to observe the clinical effect of Jiawei Yiwei decoction on acne patients with deficiency of stomach yin and deficiency of fire, and to compare the curative effect with western medicine alone. In order to explore and develop new ideas and methods for the treatment of acne vulgaris in traditional Chinese medicine, it will provide reliable prescription and medication basis for the treatment of acne in clinical practice in the future. It also opened up a new way for the treatment of acne. The research method was selected in Yuncheng traditional Chinese Medicine Hospital (December 2014-November 2015) to diagnose as "acne (deficiency of stomach and yin, deficiency of fire on inflammation)". In addition, 50 outpatients who met the criteria included in this study were randomly divided into treatment group (n = 25) and control group (n = 25). The treatment group was treated with traditional Chinese medicine plus Yiwei decoction, traditional Chinese medicine decoction, water decoction, 2 times a day, 1 dose per day; The patients in the control group were given Viamin capsules, warm boiled water, 50 mg twice a day, half an hour after meals. The course of treatment was 4 weeks. The comprehensive curative effect between the treatment group and the control group was compared with that of the control group. The therapeutic effect of skin lesions. During the treatment, avoid eating cold, spicy and other hair, pay attention to maintain emotional optimism and good rest. Results after 4 weeks of treatment, the scores of skin lesions in both groups were lower than before. The T value of the treatment group before and after treatment was 18.321 p value 0.05, the statistical difference was significant, which indicated that the therapeutic effect was significant. Comparison within the control group: the control group before and after treatment T value 13.086p value 0.05, the statistical difference is significant, indicating that the therapeutic effect is significant. Comparison between the two groups: before treatment T value 0.514. P value was 0.05, indicating that there was no statistical significance and no significant difference between the two groups before treatment. After 2 weeks of treatment, the T value of the two groups was 1.741 (p = 0.05), but there was no statistical significance between the two groups. After 4 weeks of treatment, the T value was 0.610p value 0.0020.05, there was significant difference between the two groups, and the improvement of the treatment group was higher than that of the control group, and the comprehensive curative effect of the two groups was higher than that of the control group. The total effective rate was higher than that of x2 10.068 p 0.05, which indicated that there was a significant difference in curative effect between the two groups. The therapeutic effect of the treatment group was significantly better than that of the control group. Conclusion the therapeutic effects of the treatment group and the control group were compared. This paper demonstrated the certainty and safety of the treatment of acne caused by stomach yin deficiency type by self-made Yiwei decoction, and discussed the characteristics and feasibility of traditional Chinese medicine in the treatment of acne of stomach yin deficiency type. It shows that Chinese medicine has great advantages in the long-term treatment of acne, and it is worth discussing and popularizing.
【学位授予单位】：山西中医学院
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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