凉血解毒法治疗寻常型银屑病疗效的Meta分析

发布时间：2018-01-10 03:34

本文关键词：凉血解毒法治疗寻常型银屑病疗效的Meta分析　出处：《北京中医药》2017年03期 　论文类型：期刊论文

【摘要】：目的系统评价凉血解毒法治疗银屑病的临床疗效。方法计算机检索相关期刊论文(1956-2016)、VIP全文数据库(1989-2016)、万方数据库(1990-2016)和Pub Med、EMBASE、Medline,收集所有关于凉血解毒法治疗寻常型银屑病的随机对照实验,由2名评价员共同评价纳入研究的质量,并用Rev Man5.3进行Meta分析。结果纳入9篇随机对照实验。Meta分析结果显示:凉血解毒法治疗寻常型银屑病的有效率与其他方法治疗寻常型屑病的有效率有明显差异[RR=1.20,95%CI(1.13,1.28)]。结论凉血解毒法治疗寻常型银屑病优于其他方法治疗寻常型银屑病,但由于纳入研究的方法学质量较低,故尚不能据此证实凉血解毒法治疗寻常型银屑病的疗效优于其他方法,仍需要进行严格的多中心、大样本的随机双盲对照试验,以提供高质量的临床证据。
[Abstract]:Objective to evaluate the clinical efficacy of Liangxue Jiedu method in the treatment of psoriasis. Methods we searched China Journal Full-text Database (1956-2016), VIP database (1989-2016), Wanfang database (1990-2016) and Pub Med, EMBASE, Medline, collected all of the cooling blood detoxification method in the treatment of psoriasis vulgaris with randomized controlled trials, evaluated by 2 members of the common assessment of the quality of the included studies and analysis was performed by Meta Rev Man5.3. The results included 9 randomized controlled trials of.Meta analysis results show that the method of cooling blood detoxification in the treatment of psoriasis vulgaris with efficiency and other methods to treat vulgaris chip disease efficiency have a significant difference [RR=1.20,95%CI (1.13,1.28). Conclusion blood and detoxification treatment of vulgaris psoriasis is better than other methods for the treatment of psoriasis vulgaris, but because of methodological quality is low, so it can not confirm the treatment for detoxification accordingly The efficacy of regular psoriasis is better than that of other methods. Strict multicenter, large sample randomized double blind control trials are still needed to provide high quality clinical evidence.

【作者单位】：北京中医药大学东直门医院皮肤科;
【基金】：北京中医药大学2015年度基本科研业务费项目(中青年教师类)基金资助课题(2015-JYB-JSMS091)
【分类号】：R275.9
【正文快照】： 银屑病(psoriasis)是一种常见慢性反复发作的炎症性皮肤病,其发病机制及病因尚不明确,故治疗极为困难。马栓全[1-2]认为该病多由外感风寒、风热之邪袭表,致机体营卫失和,血热内蕴,则郁久化毒,毒热壅滞,阻遏肤络,外发于肌肤。赵炳南[3]强调“内有蕴热、郁于血分”,认为血热是机

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