养血润燥祛风止痒汤治疗血虚风燥型神经性皮炎临床研究

发布时间：2018-01-10 22:23

  本文关键词：养血润燥祛风止痒汤治疗血虚风燥型神经性皮炎临床研究　出处：《黑龙江省中医药科学院》2016年硕士论文　论文类型：学位论文

  更多相关文章： 养血润燥祛风止痒汤 血虚风燥型 神经性皮炎

【摘要】：目的:观察养血润燥祛风止痒汤剂治疗血虚风燥型神经性皮炎临床疗效及不良反应,初阶探讨其作用机理,为中医治疗神经性皮炎临床研究给予依据。方法:随机选择门诊诊断为神经性皮炎且证型为血虚风燥型的患者80例,随机分为两组:治疗组和对照组。其中完成全部观察:77例,脱落:3例。对照组39例,治疗组38例。对照组给予“疗癣卡西甫丸”一次一袋(10g/袋),一日两次,治疗组给予“养血润燥祛风止痒汤剂”一日一剂,分早晚温服。观察两组患者的皮损和自觉症状的变化,同时记录不良反应,一个疗程为两周,三个疗程后给予疗效评分,用SPSS13.0软件进行统计分析。计数资料,采用X2检验,计量资料,采用t检验。结果:经比较以上两组病例性别及年龄分布均衡,具有可比性。治疗组:痊愈率10.53%,显效率50.00%,有效率36.84%总有效率97.36%;对照组:痊愈率0%,显效率33.33%,有效率41.03%总有效率74.36%.经统计学分析有显著差异(P0.05)。在减轻中医症状、皮损及自觉症状方面,治疗组明显优于对照组(P0.05)但在其他症候方面的改变,两组疗效相当。结论:养血润燥祛风止痒汤剂对血虚风燥型神经性皮炎有显著疗效,可显著的减轻患者皮损面积、厚度及瘙痒程度。养血润燥祛风止痒汤剂治疗血虚风燥型神经性皮炎安全有效,未见明显不良反应。
[Abstract]:Objective: to observe the clinical efficacy and adverse reactions of Yangxue Runzao qufeng Zhiyang decoction in treating neurodermatitis with blood deficiency and wind dryness and to explore its mechanism. Methods: 80 patients with neurodermatitis diagnosed as neurodermatitis with syndrome of blood deficiency and wind dryness were selected randomly. They were randomly divided into two groups: the treatment group and the control group, of which 77 cases were observed, 3 cases dropped out, and 39 cases were in the control group. 38 cases in the treatment group. The control group was given "tinea kasifu pills" once a bag of 10 g / bag, on 1st, the treatment group was given "nourishing blood, moistening dryness, dispelling wind and relieving itching decoction" one dose on 1st. Observe the changes of skin lesions and conscious symptoms of the two groups, and record the adverse reactions at the same time, one course of treatment is two weeks, three courses of treatment to give the curative effect score. SPSS13.0 software was used to carry out statistical analysis. Counting data, using X2 test, measuring data and t test. Results: the gender and age distribution of the above two groups were compared. In the treatment group, the cure rate was 10.53%, the effective rate was 50.00000 and the effective rate was 36.84%. The total effective rate was 97.36; The control group: the cure rate was 0, the effective rate was 33.33 and the effective rate was 41.03%. The total effective rate was 74.36.The statistical analysis showed that there were significant differences in the symptoms of traditional Chinese medicine (TCM). In terms of skin lesions and conscious symptoms, the treatment group was significantly better than the control group (P0.05), but the changes in other symptoms. Conclusion: Yangxue Runzao qufeng Zhiyang decoction has significant effect on neurodermatitis of blood deficiency and wind-dryness type, and can significantly reduce the area of skin lesions of patients. It is safe and effective to treat neurodermatitis with blood deficiency and wind dryness without obvious adverse reactions.
【学位授予单位】：黑龙江省中医药科学院
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9
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本文编号：1407055