补肾调周法治疗肾虚型多囊卵巢综合征的临床疗效观察

发布时间：2018-01-11 01:06

本文关键词：补肾调周法治疗肾虚型多囊卵巢综合征的临床疗效观察　出处：《南京中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：多囊卵巢综合征是育龄期妇女常见的妇科内分泌疾病,有明显的种族差异和地区差异,由于诸多相关因素的影响,该病的发生的人群的年龄范围扩宽,概率增高。中医角度看肾虚正为其病机之根。故此次研究主要想通过一系列有效的观察,数据分析等方法,来探讨补肾调周法用于治疗肾虚型多囊卵巢综合征的疗效确切程度并为临床积累治疗该病组方遣药灵活变化的经验,从而既可以学习一种临床研究方法,又能为临床创造更多治疗思路。方法：选择符合纳入标准的30例肾虚证型的多囊卵巢综合征患者,运用补肾调周法治疗,采用自身对照法,以三个月为一个疗程,连续观察1个疗程治疗前后的血清性激素水平,统计评估治疗前后病人内分泌改善程度,患者中医主证、次证、B超、BBT改变以及妊娠等不同方面的变化,从而对药物的疗效进行判定。结果：汇总临床数据并分析结果之后,发现采用补肾调周法治疗肾虚型的多囊卵巢综合征后的临床治愈率为23.3%,总有效率为73.3%。该法显著地改善患者的中医肾虚症候和体征,降低LH/FSH比值及雄激素水平,建立双相基础体温,恢复有排卵月经,改善B超状态,一定程度上改善了多毛座疮表现,而尚不具有统计学意义。结论：在以中药补肾调周法治疗多囊卵巢综合征的临床研究中,观察到其最终可明显改善患者的临床体征,调节内分泌情况,恢复卵巢的排卵功能等,且副作用较轻,为临床治疗PCOS提供有效的治疗方法。
[Abstract]:Objective: polycystic ovary syndrome (PCOS) is a common gynecological endocrine disease in women of childbearing age. Increase in probability. From the perspective of traditional Chinese medicine, kidney deficiency is the root of its pathogenesis. Therefore, this study mainly through a series of effective observation, data analysis and other methods. To explore the therapeutic effect of tonifying kidney and regulating weeks in the treatment of kidney deficiency polycystic ovary syndrome (PCOS) and to accumulate the experience of flexible changes of prescriptions for the treatment of this disease, so that we can learn a clinical research method. Methods: 30 cases of polycystic ovary syndrome with kidney deficiency syndrome were selected and treated by tonifying kidney and regulating week. Three months as a course of treatment, continuous observation of serum sex hormone levels before and after treatment, statistical evaluation of patients before and after treatment of endocrine improvement, patients with traditional Chinese medicine syndrome, syndrome, B ultrasound. Changes in BBT and pregnancy to determine the efficacy of the drug. Results: summary of clinical data and analysis of the results. It was found that the clinical cure rate and the total effective rate were 23.3and 73.3respectively after the treatment of polycystic ovary syndrome with kidney deficiency by tonifying the kidney and regulating the week. The method significantly improved the symptoms and signs of kidney deficiency in traditional Chinese medicine. Lowering the ratio of LH/FSH and androgen, establishing biphasic basal body temperature, recovering ovulation menstruation, improving the state of B-ultrasound, improving the appearance of hirsutism to a certain extent. Conclusion: in the clinical study of polycystic ovary syndrome treated with traditional Chinese medicine tonifying kidney and regulating week, it is observed that it can obviously improve the clinical signs and regulate the endocrine state of the patients. Recovery of ovulation function and mild side effects provide an effective method for clinical treatment of PCOS.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.9

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