参麦芩苡汤治疗中虚湿热型慢性萎缩性胃炎的临床研究

发布时间：2018-01-11 02:05

本文关键词：参麦芩苡汤治疗中虚湿热型慢性萎缩性胃炎的临床研究　出处：《南京中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:观察益气养阴,清热利湿为主要作用的参麦芩苡汤对中虚湿热型慢性萎缩性胃炎的临床疗效,并探讨其组方原理与作用机制,以期进一步总结与推广名老中医单兆伟教授治疗慢性萎缩性胃炎的经验。方法:选取2014年10月至2016年09月江苏省中医院名医堂门诊慢性萎缩性胃炎患者60例,所有患者中医辨证属于中虚湿热证。予参麦芩苡汤治疗6个月,观察治疗前后主要症状、胃镜及病理变化情况。结果:经治疗后复查胃镜及病理,60例萎缩治愈24例,治愈率40.0%,总有效率73.3%;56例肠化治愈14例,治愈率25.0%,总有效率57.1%。参麦芩苡汤加减对HP感染总有效率为26.1%,对黏膜糜烂总有效率为38.9%,对胆汁反流总有效率为63.2%。60例CAG患者治疗前后中医证候疗效进行比较,临床治愈0例,显效10例,有效43例,无效7例,总有效率88.3%。结论:以益气养阴,清热利湿为主要作用的参麦芩苡汤对中虚湿热型慢性萎缩性胃炎疗效明显,能明显改善患者胃镜病理指标及临床症状。
[Abstract]:Objective: to observe the clinical effect of Shenmai Qin Yi decoction which is mainly used to nourish qi and nourish yin and clear heat and heat for the treatment of chronic atrophic gastritis with central deficiency and dampness heat, and to explore the principle and mechanism of its composition. To further summarize and promote the old Chinese medicine professor Shan Zhaowei's experience in the treatment of chronic atrophic gastritis. Methods:. From October 2014 to September 2016, 60 patients with chronic atrophic gastritis were selected. All patients were treated with Shenmaicalin decoction for 6 months. The main symptoms, gastroscopy and pathological changes were observed before and after treatment. Results: after treatment, gastroscopy and pathology were reviewed. Among 60 cases, 24 cases were cured by atrophy, the cure rate was 40.0%, and the total effective rate was 73.3%. 14 cases were cured with intestinal metaplasia, the cure rate was 25.0 and the total effective rate was 57.1. The total effective rate of Shenmaicenyi decoction for HP infection was 26.1cm, and the total effective rate for mucosal erosion was 38.9%. The total effective rate of bile regurgitation was 63.2%. 60 cases of CAG patients were compared before and after treatment. The clinical curative effect was 0 cases, remarkable effect 10 cases, effective 43 cases, ineffective 7 cases. Conclusion: Shenmai Qinyi decoction with the main effect of supplementing qi and nourishing yin, clearing heat and promoting dampness is effective in treating chronic atrophic gastritis with central deficiency, dampness and heat. It can obviously improve the pathological index and clinical symptoms of gastroscopy.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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