“肺与大肠相表里”理论在支气管哮喘急性发作期的临床应用研究

发布时间：2018-01-11 02:27

本文关键词：“肺与大肠相表里”理论在支气管哮喘急性发作期的临床应用研究　出处：《山东中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:1.观察支气管哮喘急性发作期肠道功能失调的发生率。2.基于“肺与大肠相表里”理论,客观评价调肠法在支气管哮喘性急性发作期治疗中的应用价值,为调肠法治疗支气管哮喘急性发作期提供依据。方法:1.支气管哮喘急性发作期患者肠道功能失调发生情况的观察按照支气管哮喘急性发作期的纳入标准,选取2014年1月至2015年12月的住院患者,观察哮病发作期各证型兼有肠道功能失调的分布情况。2.调肠法在支气管哮喘急性发作期治疗中的疗效观察选取2014年1月至2015年12月的支气管哮喘急性发作期兼有肠道功能失调,中医诊断为“热哮、肠热腑实证”的患者64名,随机将患者分为观察组和对照组,观察组在西医常规治疗及饮食、生活调节的基础上加用调肠法。对照组为西医常规治疗及饮食、生活调节。对两组患者的哮病证候积分、肠热腑实证证候积分、中医证候疗效、全身激素用量及用药时间、哮喘控制测试(ACT)评分进行比较。对收集的数据进行统计学处理分析。结果:1.哮喘急性发作期患者共300例,哮喘急性发作期兼肠道功能失调的患者共207例,发生率为69.0%,其中以热哮兼肠热腑实证发生率最高为23.3%。2.调肠法在支气管哮喘急性发作期治疗中具有一定优势。(1)两组患者治疗后哮病证候积分较治疗前均有改善(P0.05);治疗后两组患者哮病证候积分比较,观察组优于对照组,差异有显著性(P0.05)。(2)两组患者治疗后肠热腑实证证候积分较治疗前均改善(P0.05);治疗后两组肠热腑实证证候积分比较,观察组优于对照组,差异有显著性(P0.05)。(3)中医证候疗效分析,观察组的总有效率明显高于对照组,差异具有显著性(P0.01)。(4)观察组激素使用量明显少于对照组,差异具有显著性(P0.01);观察组激素使用时间明显短于对照组,差异具有显著性(P0.01)。(5)两组患者哮喘控制测试(ACT)评分,治疗后较治疗前均明显改善,差异有显著性(P0.01)。治疗后两组ACT评分比较,治疗组明显高于对照组。差异具有显著性(P0.01)。结论:1.支气管哮喘急性发作期兼有肠道功能失调的发生率较高,其中以热哮兼有肠热腑实证为主要表现。2.运用调肠法能有效的缓解患者热哮兼有肠热腑实证的症状体征,改善患者的生活质量。调肠法是治疗支气管哮喘的有效治法,与单纯西医常规治疗加饮食及生活调节相比,安全有效,值得临床应用与推广。
[Abstract]:Objective 1. To observe the incidence of intestinal dysfunction in acute episode of bronchial asthma. Objective to evaluate the application value of the method of regulating intestine in the treatment of acute attack of bronchial asthma. Methods 1. Observing the incidence of intestinal dysfunction in patients with acute attack of bronchial asthma according to the inclusion criteria of acute attack of bronchial asthma. The inpatients were selected from January 2014 to December 2015. Observation on the Distribution of intestinal dysfunction in different Syndrome types of Asthma during the period of Asthma. Acute attack of asthma has intestinal dysfunction. Sixty-four patients diagnosed as "heat wheezing, intestinal heat Fu syndrome" were randomly divided into observation group and control group. The observation group was treated with routine western medicine and diet. On the basis of the adjustment of life, add the method of regulating intestine. The control group is routine treatment of western medicine and diet, life regulation. Two groups of patients with wheezing syndrome integral, intestinal heat Fu syndrome integral, TCM syndromes curative effect. The dosage of systemic hormone, the time of medication, the score of asthma control test (ACT) were compared. The collected data were analyzed statistically. Results: 1. There were 300 patients with acute asthma attack. There were 207 patients with acute attack of asthma and intestinal dysfunction, the incidence was 69.0%. Among them, the incidence rate of heat asthma combined with intestinal heat Fu syndrome is the highest 23.33.2.The method of regulating intestine has some advantages in the treatment of acute attack of bronchial asthma. After treatment, the syndrome score of the two groups was improved compared with that before treatment (P 0.05). After treatment, the observation group was better than the control group. There was a significant difference between the two groups (P0.05N. 2) after treatment, the score of the syndrome of intestinal heat in the two groups was improved compared with that before treatment (P 0.05). After treatment, the observation group was better than the control group, the difference was significant (P0.05U. 3) the total effective rate of the observation group was significantly higher than that of the control group. The use of hormone in the observation group was significantly lower than that in the control group, and the difference was significant (P 0.01). The time of hormone use in the observation group was significantly shorter than that in the control group, and the difference was significant (P 0.01). The difference was significant (P 0.01). The ACT scores of the two groups were compared after treatment. The treatment group was significantly higher than the control group. The difference was significant (P 0.01). Conclusion 1. The incidence of acute asthma with intestinal dysfunction is higher. Among them, heat wheezing has both intestinal heat and internal organs as the main performance. 2. The use of bowel regulation method can effectively alleviate the symptoms and signs of heat wheezing patients. To improve the quality of life of patients, intestinal regulation is an effective treatment for bronchial asthma, compared with routine western medicine treatment plus diet and daily life regulation, it is safe and effective, and worthy of clinical application and promotion.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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