宋立群教授治疗尿路感染用药规律的临床研究

发布时间：2018-01-11 11:28

本文关键词：宋立群教授治疗尿路感染用药规律的临床研究　出处：《黑龙江中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：通过运用SPSS19.0统计软件对宋立群教授治疗尿路感染的中药方剂进行分析,获得组方的用药规律,进而研究总结其治疗尿路感染的临床用药经验。方法：收集2012年1月至2016年2月于黑龙江中医药大学附属第一医院肾病科由宋立群教授门诊诊治的尿路感染患者病例。对纳入病例的中药方剂进行统计。运用数据库软件、SPSS19.0软件对纳入方剂进行频数分析、聚类分析,从而探讨宋立群教授治疗尿路感染的用药规律。结果：根据病例纳入标准和排除标准,获得纳入病例300例。共使用药物196味,使用总频数5323次。使用频数40次以上有35味药物,占总用药的76.57%。其中黄芪、焦白术、半枝莲、白花蛇舌草、山楂、神曲、麦芽、土茯苓、党参、蒲公英、炙甘草、瞿麦、篇蓄、白茅根、石韦是治疗尿路感染的核心药物。药物药性以平、寒为主。药物药味以甘、苦为主。按照用药频数排列,药物归经最常见的是脾经、胃经、肝经、肺经、肾经。根据药物聚类分析结果,得到常用药对组合13组。结论：1.统计得出治疗尿路感染的核心药物为：黄芪、焦白术、半枝莲、白花蛇舌草、山楂、神曲、麦芽、土茯苓、党参、蒲公英、炙甘草、瞿麦、篇蓄、白茅根、石韦。2.治疗尿路感染药物药性以平、寒为主,药味方面以甘、苦为主,在归经上主要归脾经、胃经、肝经为主。3.治疗尿路感染以补虚药、清热药、消食药、利水渗湿药、止血药、活血化瘀药为主体。4.经过聚类分析得出治疗尿路感染的13个常用药物组合。5.尿路感染为虚实夹杂之证,往往兼有湿热瘀毒蕴结和正气亏虚。在治疗上应辨虚实,标本缓急,采用清补兼施之法。
[Abstract]:Objective: to analyze the prescription of traditional Chinese medicine used by Professor Song Liqun in the treatment of urinary tract infection by using SPSS19.0 software, and to obtain the rule of prescription. Then the clinical experience in the treatment of urinary tract infection was summarized. Methods:. Cases of urinary tract infection were collected from January 2012 to February 2016 in the Renal Department of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine. Use database software. The frequency analysis and cluster analysis were carried out by SPSS19.0 software to explore the rule of drug use by Professor Song Liqun in the treatment of urinary tract infection. Results: according to the criteria of inclusion and exclusion of cases. A total of 196 drugs were used, and the total frequency was 5323 times. 35 drugs were used more than 40 times, accounting for 76.57.Astragalus membranaceus and Atractylodes macrocephala were used. Scutellaria chinensis, Hawthorn, Dianqu, malt, Poria cocos, Codonopsis, dandelion, grilled Glycyrrhiza, Dixiao, Prunus, Roots, Shiwei are the core drugs for the treatment of urinary tract infection. According to the frequency of medicine, the most common drugs are spleen, stomach, liver, lung, kidney. According to the results of drug cluster analysis. The results showed that the core drugs for the treatment of urinary tract infection were Astragalus membranaceus, Atractylodes macrocephala, Scutellaria Scutellariae, Hedyotis, Hawthorn, Shenqu, malt, Poria cocos, and Codonopsis pilosula. Dandelion, Radix Glycyrrhiza, Dianmai, Zhumu, Baomaogan, Shiwei. 2. The drugs used to treat urinary tract infection are flat, cold, sweet and bitter in medicine taste, and mainly belong to spleen and stomach on the return of meridian. Liver meridian is the main treatment of urinary tract infection with tonifying drugs, heat-clearing drugs, anti-eating drugs, water and dampness medicine, hemostatic drugs. After cluster analysis, 13 common drug combinations for the treatment of urinary tract infection were obtained. 5. Urinary tract infection is the syndrome of deficiency and solid inclusion. Often have both dampness and heat stasis toxin accumulation knot and deficiency of qi.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R249;R277.5

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