基于复杂网络分析技术对针灸治疗心系疾病用穴规律的研究

发布时间：2018-01-11 15:07

本文关键词：基于复杂网络分析技术对针灸治疗心系疾病用穴规律的研究　出处：《成都中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：基于复杂网络分析技术对古今针灸治疗心系疾病的文献进行研究,总结针灸治疗该系疾病的用穴规律,证实复杂网络方法的可行性,并为临床选穴提供依据及建议。方法：采集针灸治疗心系疾病的古代及现代文献。参照《中医病证分类与代码》和林昭庚主编的《中西医病名对照大辞典》,确定心系疾病对应的古代病名及现代病名。古代文献以《中国针灸文献提要》为基础进行全面采集。现代文献通过计算机检索与手工检索相结合的方法进行采集,纳入针灸处方中包含十四经腧穴,以针刺、电针、艾灸为主要干预手段的临床研究文献。通过严格的数据筛选后,录入合格文献,建立心系疾病针灸文献数据库及腧穴数据库,构建腧穴-腧穴网络,运用复杂网络方法对针灸治疗心系疾病的穴位重要性进行评估,发现有效穴位对,提取核心穴组,同时根据频次统计与社团划分探索针灸治疗该系疾病的经络和特定穴使用规律。结果：古代腧穴-腧穴网络穴位节点共91个。度数排名前列的腧穴为神门、大陵、内关、心俞、巨阙,介数中心性排名前列的腧穴为心俞、大陵、中冲、内关、神门,特征向量中心度排名位于前列的穴位为神门、大陵、巨阙、内关、足通谷,使用频次排名前列的腧穴为心俞、巨阙、大陵、内关、神门。核心穴组包括神门、大陵等14个穴位。针灸处方选取经络广泛分布于十四经,以手厥阴心包经选取频次最多。特定穴选用最多的为五输穴的输穴,其次为原穴和交会穴。社团主要划分为特定穴及胸腹部穴位。现代腧穴-腧穴网络穴位节点共83个,度数排名前列的腧穴为内关、心俞、膻中、神门、厥阴俞,介数中心性排名前列的腧穴为内关、阳陵泉、心俞、神门、膻中,特征向量中心度排名位于前列的穴位为内关、心俞、膻中、神门、三阴交,使用频次排名前列的腧穴为内关、心俞、膻中、神门、足三里。核心穴组包括心俞、内关等41个穴位。针灸处方选取经络广泛分布于十四经,以手厥阴心包经选取频次最多。特定穴选用最多的为络穴,其次为八脉交会穴与背俞穴。社团主要划分为特定穴及心经、心包经穴位。结论：古今腧穴-腧穴网络均符合小世界和无标度特性。针灸治疗心系疾病所选择的穴位遵循“循经取穴”规律,并且重视局部腧穴和特定穴的选取。穴位所属经络与特定穴对社团的划分有重要意义。治疗心系疾病时,选穴宜分清主次,围绕腧穴-腧穴网络中的重要穴位节点进行配穴,选用核心穴组,以发挥腧穴协同作用的最大疗效。
[Abstract]:Objective: analysis of the complex network technology on the ancient and modern literature of acupuncture in the treatment of heart diseases were studied based on the summary of acupuncture treatment of the disease with points of law, confirm the feasibility of complex network methods, and provide basis and suggestion for clinical acupoint selection. Methods: collecting ancient acupuncture treatment heart disease and modern literature. According to < syndrome Chinese classification and code > and < the editor of Zhao Geng medicine and disease control dictionary >, determine the heart disease corresponding to the ancient name of disease and modern disease. Ancient literature in "China acupuncture literature as the basis for a comprehensive collection of summary >. Modern literature collection and manual retrieval method through the combination of the computer retrieval in acupuncture the prescription consists of fourteen acupoints, acupuncture, electroacupuncture, moxibustion for clinical research literature major interventions. Through rigorous screening data, input the qualified literature to establish the system. In the literature of acupuncture and moxibustion and acupoints database database, construction of acupoints - acupoints network, using the complex network method of acupuncture in the treatment of heart disease to assess the importance of acupuncture points, find effective acupoints to extract the core point group, at the same time, according to the frequency statistics and association rules into exploring the use of acupuncture treatment of the disease. Results: the specific acupoints of meridians and acupoints in ancient times - network node point total of 91 points. Points degree ranked the forefront of the God door, daling, Neiguan and Xinshu acupoint, Juque, betweenness centrality ranking for BL15, daling, blunt, Neiguan, Shenmen, eigenvector centrality ranking at the forefront of the acupoints of Shenmen, daling, Neiguan, Juque, foot through the valley, ranking as the frequency of use of acupoint Xinshu, Juque, daling, Neiguan, Shenmen acupoint group. The core including the door of God, the 14 acupoints Daling. Acupuncture prescription selected meridian is widely distributed in fourteen, to Pericardium meridian. The most frequently selected specific points which are used most often to point lost five transport points, followed by the original point and intersection point. The community is mainly divided into specific acupoints of thoracic and abdominal acupoints. Modern acupoints - acupoints network node of a total of 83 points, ranking as the degree of acupoint Neiguan and Xinshu, mutton in the door of God, jueyinshu acupoint, betweenness centrality ranking 6, Yanglingquan, BL15, Shenmen, danzhong, eigenvector centrality at the top of the rankings for acupoint Xinshu, Neiguan, danzhong, Shenmen, Sanyinjiao acupoints, the frequency of use of ranking 6, heart Yu, danzhong, Shenmen, Zusanli acupoint group. The core including BL15, 41 acupoints Neiguan. Acupuncture prescription meridian is widely distributed in the fourteen selected by the pericardium meridian selected most frequently. Specific points which are used most often as a complex point, followed by eight confluence points and back Shu points. The main community divided into specific Acupoint and heart, pericardium meridian acupoint and acupoint - acupoints. Conclusion: the network meets the small world and scale-free characteristics. Acupuncture treatment of heart diseases selected points follow the "acupoint" rules, and pay attention to selection of local acupoints and specific points. The points are important channels and specific points of division community. Treatment of heart disease, acupoints should distinguish primary and secondary, with points around the important points in the network node points - points, selection of the core point group, with the greatest effect play synergistic effect of acupoints.

【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.1

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